Recently, several new promising modifications have been introduced to clinical practice that may simplify and optimize IVF outcome. In the present opinion paper we present a simplified approach to controlled ovarian hyperstimulation protocol (COH), which combines the benefits of the ultrashort flare GnRH agonist/GnRH antagonist protocol and the personalized tailored mode and timing of ovulation...

We read with great interest the Commentary of Griesinger and Kolibianakis (2012) about scheduling oocyte retrieval in GnRH antagonist cycles. Recently, the results of a randomized trial by our group were published, reporting a significant decrease in oocyte retrieval during weekend days following administration of estradiol valerate in the luteal phase of the cycle prior to the stimulated cycle...

BACKGROUND The role of stress in reproduction, particularly during treatment for infertility, has been of considerable interest; however, few studies have objectively measured stress and anxiety over the course of the IVF cycle or compared the experience of first-time and repeat patients. METHODS This prospective cohort pilot study enrolled 44 women undergoing IVF at a university-based clinic...

Abstract Study question To explore whether prolonged hCG-ovum pickup(hCG-opu) interval improves assisted reproductive technology outcomes. Summary answer The clinical pregnancy rates can be increased by prolonging the hCG-opu interval, which would help develop more reasonable time schedules for fertility centers and patients. What is known already hCG-OPU greatly affects ART success, allows to ...

The cryopreservation of immature GV oocytes by vitrification is offering attractive perspectives, since they represent an important pool of germ cells for women undergoing IVM cycles, or at risk of infertility for OHSS or PCOs, particularly those poor responders to gonadotropin stimulation, or in case of cancer. Therefore, it becomes necessary to optimize both cryopreservation technique as well...

OBJECTIVE This study measured serum and follicular fluid (FF) levels of biopterin, neopterin, vascular endothelial growth factor (VEGF), and macrophage colony-stimulating factor (M-CSF) in patients receiving mild ovarian stimulation for oocyte retrieval. PATIENTS AND METHODS Infertile patients who underwent ovarian stimulation were divided into the following: Group 1, no oocyte retrieval (n =...