In the accompanying article by Santos et al published in this issue of the American 14 Journal of Physiology: Cell Physiology (8) the authors tested the hypothesis that the V15 type ATPase was present and functional in the NE. The authors established that the 16 nuclear pH is acidic, pH gradients across the nuclear membrane were bafilomysin and 17 concanamycin sensitive and that the V-type ATPa...

Background: Gestational diabetes mellitus (GDM), a common medical complication of pregnancy, is defined as “any degree of glucose intolerance with onset or first recognition during pregnancy. Risk factors for GDM: a previous GDM or prediabetes, a family history revealing a first degree relative with type 2 diabetes, maternal age(>35 y), ethnic background, being overweight, a previous pregnancy ...

In this paper we examine the convergence rates in an adaptive version of an orthonormalization method for approximating the conformal map ping f of an annular region A onto a circular annulus In particular we consider the case where f has an analytic extension in compl A and for this case we determine optimal ray sequences of approximants that give the best possible geometric rate of uniform co...

A projective algebraic manifold M is a complex manifold in certain projective space CPm, m ≥ dimC M = n. The hyperplane line bundle of CPm restricts to an ample line bundle L onM . The bundle is a polarization onM . Suppose g is a Kähler metric on M . We say g is a polarized Kähler metric with respect to L, if the corresponding Kähler form represents the first Chern class c1(L) of L in H 2(M,Z)...

Air is our main contact with the environment in which wefind ourselves. Every day, we breathe in 15 kg of air; that’s more than our daily food intake. Air, in cities and confined environments where houses are really close together, consists of particles of different sizes charged of chemical pollutants. The finer particles will come into contact with the alveoli and will allow some pollutants g...

A multiobjective optimization problem which focuses on parallel machines scheduling is considered. This problem consists of scheduling n independent jobs onm identical parallel machines with release dates, due dates, and sequence-dependent setup times. The preemption of jobs is forbidden. The aim is to minimize two different objectives: makespan and total tardiness. The contribution of this pap...