نتایج جستجو برای: oligomer
تعداد نتایج: 4193 فیلتر نتایج به سال:
A synthetic scaffold that mimics a peptide β-strand has been designed and synthesised based on a 1,3-phenyl-linked hydantoin oligomer. The conformational preferences of this oligomer were investigated using molecular modelling and solution NMR experiments and suggest a planar conformation that accurately mimics the i, i + 2 and i + 4 residues of a peptide β-strand.
Hydrophilic polymers were attached to lysozyme by a combination of grafting-to and grafting-from approaches using RAFT polymerization. A hydrophilic oligomer was synthesized, and attached to the protein. The protein-oligomer hybrid contained the RAFT end group, enabling chain extension in solution. Lysozyme maintained activity throughout this process.
Several protein conformational disorders (Parkinson and prion diseases) are linked to aberrant folding of proteins into prefibrillar oligomers and amyloid fibrils. Although prefibrillar oligomers are more toxic than their fibrillar counterparts, it is difficult to decouple the origin of their dissimilar toxicity because oligomers and fibrils differ both in terms of structure and size. Here we r...
In the wood furniture and flooring industry, protective aesthetic properties of final product often rely, at least partially, on coatings applied to surface. For flat surfaces, UV-cured are preferred due their many advantages, such as fast curing times, low volatile organic compound (VOC) emissions, energy consumption high crosslinking densities. To increase durability interior products, behavi...
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