نتایج جستجو برای: olfactory ensheathing cell
تعداد نتایج: 1703425 فیلتر نتایج به سال:
Herein, we assessed the effect of full native peptide amyloid-beta (Aβ) (1-42) and its fragments (25-35 35-25) on tissue transglutaminase (TG2) isoforms (TG2-Long TG2-Short) expression levels olfactory ensheathing cells (OECs). Vimentin glial fibrillary acid protein (GFAP) were also studied. The pre-treatment with indicaxanthin from Opuntia ficus-indica fruit TG2 isoforms, cell viability, total...
Background: Olfactory ensheathing glia (OEG) has been shown to have a neuroprotective effect after being transplanted in rats with spinal cord injury. This study was conducted to determine the possible beneficial results of olfactory mucosa transplantation (OMT) which is a source of OEG on functional recovery and axonal regeneration after transection of the sciatic nerve. Methods: In this study...
Transcription factor SOX10 plays a role in the maintenance of progenitor cell multipotency, lineage specification, and cell differentiation and is a major actor in the development of the neural crest. It has been implicated in Waardenburg syndrome (WS), a rare disorder characterized by the association between pigmentation abnormalities and deafness, but SOX10 mutations cause a variable phenotyp...
Kallmann's syndrome is caused by the failure of olfactory axons and gonadotropin-releasing hormone (GnRH) neurons to enter the embryonic forebrain, resulting in anosmia and sterility. Sox10 mutations have been associated with Kallmann's syndrome phenotypes, but their effect on olfactory system development is unknown. We recently showed that Sox10 is expressed by neural crest-derived olfactory e...
Olfactory ensheathing cell (OEC) transplantation is a candidate cellular treatment approach for human spinal cord injury (SCI) due to their unique regenerative potential and autologous origin. The objective of this study was, through a meta-epidemiologic approach, (i) to assess the efficacy of OEC transplantation on locomotor recovery after traumatic experimental SCI and (ii) to estimate the li...
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