نتایج جستجو برای: olfactory disorder

تعداد نتایج: 617987  

Journal: :Romanian Journal of Rhinology 2023

Abstract Pneumosinus dilatans (PSD) is a rare disorder that causes aberrant paranasal sinus dilation. typically benign and asymptomatic, without any evidence of bone destruction or pathologic changes in the underlying mucosa. Localized discomfort, headaches, facial paraesthesia deformities, sensory deficits, olfactory loss, ocular abnormalities are common complaints. The diagnosis PSD confirmed...

Journal: :American journal of human genetics 2013
Veronique Pingault Virginie Bodereau Viviane Baral Severine Marcos Yuli Watanabe Asma Chaoui Corinne Fouveaut Chrystel Leroy Odile Vérier-Mine Christine Francannet Delphine Dupin-Deguine Françoise Archambeaud François-Joseph Kurtz Jacques Young Jérôme Bertherat Sandrine Marlin Michel Goossens Jean-Pierre Hardelin Catherine Dodé Nadege Bondurand

Transcription factor SOX10 plays a role in the maintenance of progenitor cell multipotency, lineage specification, and cell differentiation and is a major actor in the development of the neural crest. It has been implicated in Waardenburg syndrome (WS), a rare disorder characterized by the association between pigmentation abnormalities and deafness, but SOX10 mutations cause a variable phenotyp...

Journal: :Journal of neural transmission. Supplementum 2006
H W Berendse M M Ponsen

The association of Parkinson's disease (PD) with an impaired sense of smell was first reported about thirty years ago. Since then, it has become quite firmly established that olfactory dysfunction is one of the first and most prevalent clinical manifestations of this disorder. Recent data from an ongoing prospective study indicate that otherwise unexplained hyposmia in first degree relatives of...

ژورنال: طب جنوب 2020
Asghari , Masoud, Bakhshai , Mehdi,

Background: Olfaction plays an important role in human life and promotes quality of life through understanding various odors. Nasal polyps are among the common causes of olfactory impairment. There are many different treatment options for polyps most notably the diagnosis and elimination of underlying causes. Some polyps do not respond to medication therapy or they relapse, and therefore requir...

Journal: :Human molecular genetics 2011
Wanda S Layman Elizabeth A Hurd Donna M Martin

CHARGE is a multiple congenital anomaly disorder and a common cause of pubertal defects, olfactory dysfunction, growth delays, deaf-blindness, balance disorders and congenital heart malformations. Mutations in CHD7, the gene encoding chromodomain helicase DNA binding protein 7, are present in 60-80% of individuals with the CHARGE syndrome. Mutations in CHD7 have also been reported in the Kallma...

Journal: :Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995
R L Doty S M Bromley M B Stern

Since olfactory dysfunction is among the first signs of idiopathic Parkinson's disease (PD), olfactory testing may aid in the early of 'preclinical' diagnosis of this disorder. Indeed, the proportion of early-stage PD patients with olfactory dysfunction appears to be greater than the proportion of early-stage PD patients exhibiting some of the cardinal signs of PD. Because olfactory function va...

Journal: :Cukurova Medical Journal 2021

Purpose: Several atypical presentations of COVID-19 like anosmia, conjuctivitis, and gastrointestinal findings are seen in the literature. The purpose this study was to investigate common symptoms among patients admitted otorhinolaryngology (ENT) outpatient clinic.
 Materials Methods: This case series conducted with 49 who applied hospital between April 1, 2020 30, 2020. Common otolaryngol...

2017
Miho Tsuruta Toru Takahashi Miki Tokunaga Masanori Iwasaki Shota Kataoka Satoko Kakuta Inho Soh Shuji Awano Hiromi Hirata Masaharu Kagawa Toshihiro Ansai

BACKGROUND Pathologic subjective halitosis is known as a halitosis complaint without objective confirmation of halitosis by others or by halitometer measurements; it has been reported to be associated with social anxiety disorder. Olfactory reference syndrome is a preoccupation with the false belief that one emits a foul and offensive body odor. Generally, patients with olfactory reference synd...

Journal: :Molecular and cellular neurosciences 2003
Deborah R S Cohen Valéry Matarazzo Amy M Palmer Yajun Tu Ok-Hee Jeon Jonathan Pevsner Gabriele V Ronnett

Rett syndrome, a neurodevelopmental disorder hypothesized to be due to defective neuronal maturation, is a result of mutations in the mecp2 gene encoding the transcriptional repressor methyl-CpG binding protein (MeCP2). We utilized the olfactory system, which displays postnatal neurogenesis, as a model to investigate MeCP2 expression during development and after injury. MeCP2 expression increas...

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