A stereoselective synthesis of (25S)-Δ(1)-, (25S)-Δ(1,4)-, (25S)-Δ(1,7)-, (25S)-Δ(8(14))-, (25S)-Δ(4,6,8(14))-dafachronic acid, methyl (25S)-Δ(1,4)-dafachronate and (25S)-5α-hydroxy-3,6-dioxocholest-7-en-26-oic acid is described. (25S)-Δ(1,4)-Dafachronic acid and its methyl ester are natural products isolated from corals and have been obtained by synthesis for the first time. (25S)-5α-Hydroxy-3...

The viscid exudate found on fronds o f the fern, Cheilanthes kaulfussii, consists of terpenoids in which flavonoid aglycones are dissolved. One of the terpenes is shown to be em-kaur-16-en-19-oic acid. The farinose frond exudate of Notholaena pallens contains this acid as the major constituent and its 3 /?-hydroxy derivative, together with flavonoid aglycones as minor components. In N. incana, ...

Islam is a way of life which not only affects the social and personal aspects human but also plays significant part in political economic decisions people. Empirical studies on chief determining factors growth have neglected effect Islamicity growth. This study expands upon recent literature Islamicity. By using indices data for first time, this provides brand-new viewpoint nexus world, focusin...

Two new beta-sitosterol esters have been isolated from the flowers of Punica granatum Linn. (Punicaceae) along with the known compounds n-tricosane (3), n-heptacosanyl n-hexanoate (4), olean-5,12-dien-3beta-ol-28-oic acid (5), and olean-12-en-3beta-ol-28-oic acid (6). The structures of the new phytosterols have been elucidated as stigmast-5-en-3beta-ol-3beta-dodecanoate (beta-sitosterol laurate...

Two minor triterpenoid saponins, ardisicrenoside G [3 beta-O-{alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->4)- [beta-D-glucopyranosyl-(1-->2)]-alpha-L-arabinopyranosyl}-16 alpha,28-dihydroxyolean-12-en-30-oic acid] and ardisicrenoside H [3 beta-O-{beta-D-xylopyranosyl-(1-->2)-beta-D- glucopyranosyl-(1-->4)-[beta-D-glucopyranosyl-(1-->2)]-alpha-L- arabinopyranosyl}-16 alpha,28-dihy...

Penifulvins B-E (2-5), four new sesquiterpenoids with a dioxa[5.5.5.6]fenestrane ring system, have been isolated from cultures of an isolate of Penicillium griseofulvum (NRRL 35584), together with a new silphinene derivative, 12-hydroxysilphinene-15-oic acid (6). Penifulvins B-E (2-5) are oxidized analogues of penifulvin A (1) and were identified by analysis of NMR and MS data. 12-Hydroxysilphi...

The ethyl acetate soluble fraction from the roots of Sanguisorba tenuifolia was found to have a hypoglucemic effect in alloxan-induced diabetic rats. Two new triterpenoids, identified as 2-oxo-3β,19α-dihydroxyolean-12-en-28-oic acid β-D-gluco-pyranosyl ester (1) and 2α,19α-dihydroxy-3-oxo-12-ursen-28-oic acid β-D-glucopyranosyl ester (4) were isolated from this fraction, along with thirteen kno...

Multiple effects of ozone are a prerequisite for its use in the complex therapy inflammatory bowel diseases. Our aim was to analyze and 5-aminosalicylic acid (5-ASA) oxazolone-induced colitis (OIC) upon innate immunity functions.
 OIC modeled 72 male Wistar rats weighing 24020 g by two-stage application oxazolone solution. Ozone at dose 0.05 mg/kg, as part ozone-oxygen mixture, injected in...

Objective: <i>Jowiseunggi-tang</i> (JWSGT) is a traditional herbal medicine commonly used for purgative activity in constipation. This study evaluates JWSGT the treatment of opioid-induced constipation (OIC), most common and debilitating gastrointestinal effect opioid use.Methods: A 64-year-old man with floor mouth cancer was hospitalized OIC, administered orally twice day 10 days, ...