background: the risk of infection by transfusion-transmitted viruses has been reduced remarkably. however, a zero-risk blood supply is still desirable. the screening for antibody to hbc (anti-hbc) has been shown as an alternative test for the detection of hbv infection. objective: the main aim of this study was to evaluate hbv infection markers and the potential value of anti-hbc testing of blo...

INTRODUCTION Despite significant improvement in Anti-HBV vaccination and treatment, HBV infection continues to be a major global health problem. It has been reported that as much as 350 million carriers exist in the world and about one million of them will die annually (1). The prevalence of HBV infection in Iran ranged between 2.7 to 7.2 %, which declined below 2% following national vaccinatio...

OBJECTIVE Hepatitis B virus (HBV) and HIV are endemic infections in many African countries. The objectives of this study were to determine the levels of exposure to, and protection from, HBV, as well as the prevalence of HIV/HBV co-infection and the response of HBV to highly active anti-retroviral therapy (HAART) in a cross-section of HIV-infected patients in north-eastern South Africa. STUDY...

BACKGROUND The association between mutations in the hepatitis B surface antigen (HBsAg) gene and the occurrence of occult HBV (OBI) in patients has not been studied adequately to determine if the two are correlated. The current study was aimed to investigate HBsAg mutations, the genotype of HBV and co-infection with HCV in OBI in the central part of Iran to determine any possible associations. ...

PURPOSE: To determine prevalence of positive HBV DNA in liver tissue samples in patients with chronic HCV infection (CHCV) and to investigate whether there is an association between it and underlying clinical condition. METHODE: For the period 2004 – 2010 in the Gastroenterology Clinic at the Military Medical Academy – Sofia, 96 patients CHCV (77% males, 23% females, mean age 50, 5 ± 10, 02 yea...

Occult HBV infection is defined as the presence of hepatitis B virus (HBV) DNA in blood or liver tissues in patients negative for Hepatitis B surface Antigen (HBsAg). Those patients may or may not be positive for HBV antibodies. The objective of this study is to determine the presence or absence of HBV DNA in the serum samples from HBsAg negative blood donors. In addition we aimed to assess the...

conclusions this study showed a low rate of isolated anti-hbc and occult hbv infection in hd patients. it can be due to improvement of people’s knowledge about hbv transmission routes, hbv vaccination of hd patients and regular surveillance of hbv infection. results a hundredpatients with a mean age of 58.5 ± 16.1 years were enrolled in this study. in total, 56.7% were male and 43.3% female. an...

Background and Aim: Occult hepatitis B virus (HBV) infection is an incompletely understood condition. There no data about occult HBV in sero-discordant couples. We attempted to find out the prevalence of OBI this cohort formulate guidelines for vaccination. Methods: 40 couples were enrolled. DNA (quantitative), Anti HBc HBs titre (quantitative) done. was defined as positivity without detectable...

BACKGROUND Hepatitis B virus (HBV) and tuberculosis (TB) represent major public health problems. There is currently little data on HBV infection among TB patients with and without human immunodeficiency virus (HIV). OBJECTIVES To assess HBV prevalence among TB patients with and without HIV. STUDY DESIGN From April 2008 to March 2010, a cross-sectional study was conduct among TB patients att...

BACKGROUND Data on prevalence and incidence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in Rwanda are scarce. METHODS HBV status was assessed at baseline and Month 12, and anti-HCV antibodies at baseline, in a prospective cohort study of HIV-infected patients in Kigali, Rwanda: 104 men and 114 women initiating antiretroviral therapy (ART) at baseline, and 200 women not ye...