background: trichophyton tonsurans is one of the dermatophyte fungi which invades the skin and hair of human. several properties of this fungus have been investigated so far. however a few studies were carried out in the field of molecular biology of this fungus. in the present study, we tried to identify the squalene epoxidase gene which is related to synthesis of ergosterol in this fungus. me...

DNA methylation at CpG dinucleotides can significantly increase the rate of cytosine-to-thymine mutations and the level of sequence divergence. Although the correlations between DNA methylation and genomic sequence evolution have been widely studied, an unaddressed yet fundamental question is how DNA methylation is associated with the conservation of individual nucleotides in different sequence...

A homogeneous preparation of cyclic CMP phosphodiesterase (Helfman, D. M., Shoji, M., and Kuo, J. F. (1981) J. Biol. Chem. 256, 6327-6334) was found to catalyze the hydrolysis of both pyrimidine and purine cyclic 2':3'- and 3':5'-nucleotides. Hydrolysis of cyclic 2':3'-nucleotides resulted in the formation of both 2'- and 3'-nucleotides, although relative amounts of the products were variable. ...

Abstract The first confirmed case of African swine fever (ASF) in Vietnam was officially reported February 2019. To date, the ASF virus (ASFV) has been detected all 63 cities/provinces Vietnam. In order to get a better understanding potential role EP402R gene grouping ASFV serotypes, thirty sequences genes (accession numbers: MN711757-86) from North Central Coast and 68 well-known references se...