نتایج جستجو برای: normal tension glaucoma ntg

تعداد نتایج: 636676  

2017
Akvile Daveckaite Evelina Grusauskiene Kestutis Petrikonis Antanas Vaitkus Lina Siaudvytyte Ingrida Januleviciene

PURPOSE Only a few studies have analyzed the potential link between glaucoma and cognitive function impairment. They have found controversial results. This study aims to perform quick cognitive function assessment with clock drawing test (CDT) using two different scoring systems and compare between normal tension glaucoma (NTG) and cataract patients. METHODS Totally, 30 NTG and 30 patients wi...

2009
Jutaro Nakamura Akira Meguro Masao Ota Eiichi Nomura Tadayuki Nishide Kenji Kashiwagi Fumihiko Mabuchi Hiroyuki Iijima Kazuhide Kawase Tetsuya Yamamoto Makoto Nakamura Akira Negi Takeshi Sagara Teruo Nishida Masaru Inatani Hidenobu Tanihara Makoto Aihara Makoto Araie Takeo Fukuchi Haruki Abe Tomomi Higashide Kazuhisa Sugiyama Takashi Kanamoto Yoshiaki Kiuchi Aiko Iwase Shigeaki Ohno Hidetoshi Inoko Nobuhisa Mizuki

PURPOSE Toll-like receptor 2 (TLR2) is a transmembrane receptor that mediates immune responses to exogenous and endogenous ligands, and interacts with heat-shock proteins, which are reportedly involved in normal tension glaucoma (NTG). We investigated whether TLR2 polymorphisms are associated with NTG. METHODS 200 Japanese patients with NTG and 128 healthy Japanese controls were recruited. We...

Journal: :The British journal of ophthalmology 1998
L Fontana D Poinoosawmy C V Bunce C O'Brien R A Hitchings

AIMS This study was designed to investigate pulsatile ocular blood flow (POBF) in normal tension glaucoma (NTG) patients and in normal controls. NTG patients with unilateral field loss were evaluated to compare POBF values between eyes with and without field loss. METHODS POBF measurements from more than 1500 subjects were collected during a period of 6 months from six optometric centres. Sub...

Journal: :Investigative ophthalmology & visual science 2005
Tin Aung Tayebeh Rezaie Koji Okada Ananth C Viswanathan Anne H Child Glen Brice Shomi S Bhattacharya Ordan J Lehmann Mansoor Sarfarazi Roger A Hitchings

PURPOSE To investigate the clinical features of subjects with glaucoma with the E50K mutation in the optineurin (OPTN) gene and to compare the onset, severity, and clinical course of these patients with a control group of subjects with glaucoma without this mutation. METHODS The phenotype of well-characterized subjects from Moorfields Eye Hospital, London, who had been identified as carrying ...

Journal: :American journal of ophthalmology 2013
Peter Wostyn Veva De Groot Debby Van Dam Kurt Audenaert Peter Paul De Deyn

PURPOSE To evaluate the evidence supporting a role for senescent changes in cerebrospinal fluid (CSF) circulatory physiology in the pathogenesis of normal-tension glaucoma (NTG). DESIGN Literature review and personal perspective of the authors. METHODS Analysis of selected articles in the peer-reviewed literature with interpretation and perspective. RESULTS Recent studies have reported th...

Journal: :Investigative ophthalmology & visual science 2015
Akira Sawada Jonathan A Rivera Daisuke Takagi Takashi Nishida Tetsuya Yamamoto

PURPOSE To determine the probability of an eye with normal tension glaucoma (NTG) progressing to legal blindness under standard ophthalmic care. METHODS Patients diagnosed with NTG (n = 382) between 1985 and 2007 at Gifu University Hospital were followed for at least 5 years under standard ophthalmic care. The collected data included the best-corrected visual acuity (BCVA), intraocular pressu...

2017
Fumihiko Mabuchi Nakako Mabuchi Yoichi Sakurada Seigo Yoneyama Kenji Kashiwagi Hiroyuki Iijima Zentaro Yamagata Mitsuko Takamoto Makoto Aihara Takeshi Iwata Kazuhide Kawase Yukihiro Shiga Koji M Nishiguchi Toru Nakazawa Mineo Ozaki Makoto Araie

To investigate the association between the additive effects of genetic variants associated with intraocular pressure (IOP) and IOP, vertical cup-to-disc ratio (VCDR), and high tension glaucoma (HTG) or normal tension glaucoma (NTG) as phenotypic features of primary open-angle glaucoma (POAG), and to evaluate the clinical usefulness of the additive effects of IOP-related genetic variants for pre...

2015
Jong Chul Han Da Ye Choi Changwon Kee

Purpose. To evaluate the different characteristics in superior segmental optic hypoplasia (SSOH) and normal tension glaucoma (NTG) with superior retinal nerve fiber layer (RNFL) defect (NTG-SRD) compared to normal control using cirrus optical coherence tomography (OCT). Methods. SSOH eyes and NTG-SRD eyes were reviewed. The peripapillary RNFL (pRNFL) and ganglion cell inner plexiform layer (GCI...

Journal: :Investigative ophthalmology & visual science 2011
Joon Mo Kim Seok Hwan Kim Ki Ho Park So Young Han Hyoung Sub Shim

PURPOSE To investigate whether Helicobacter pylori infection is associated with normal tension glaucoma (NTG). METHODS One hundred consecutive NTG patients (group 1) from an outpatient glaucoma clinic were enrolled. Medical records of the 88 control participants (control 1) of the outpatient clinic, and 104 NTG patients (group 2) and 1116 healthy controls (control 2) (1220 subjects in total) ...

Journal: :Molecular vision 2006
Seok Hwan Kim Ji Yeon Kim Dong Myung Kim Hyun Su Ko Sung Yeun Kim Taiwoo Yoo Seung Sik Hwang Sung Sup Park

PURPOSE In normal tension glaucoma (NTG), intraocular pressure is within normal the range; thus, some mechanism other than increased pressure contributes to the optic neuropathy. Endothelin may be an important contributor to the development of the optic neuropathy characteristic of glaucoma. We investigated whether polymorphisms of the endothelin-1, endothelin receptor type A, and endothelin re...

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