Intr Maintaining the patency of arterial lines is essential for obtaining accurate physiological measurements, enabling blood sampling and minimising the time, expense and patient discomfort incurred by line replacement. HS is commonly used to maintain and prolong arterial line patency. In 2008, a National Patient Safety Agency alert advised organisations to minimise its use for this purpose fo...

OBJECTIVE Liver failure can occur as a consequence of the systemic inflammation after acute pancreatitis. We assessed the effect of volume repositioning with hypertonic saline solution or normal saline on hepatic cytokine production and the expression of heat-shock proteins and apoptotic proteins after acute pancreatitis. METHODS Wistar rats were divided in four groups: C - control animals th...

STUDY OBJECTIVE We seek to determine whether an initial intravenous bolus of 5% dextrose in normal saline solution compared with normal saline solution will lead to a lower proportion of hospitalized patients and a greater reduction in serum ketone levels in children with gastroenteritis and dehydration. METHODS We enrolled children aged 6 months to 6 years in a double-blind, randomized contr...

Normal saline is the most popular agent used during endoscopic submucosal injection. However, endoscopists have never identified an optimal submucosal injection solution, which is not only safe and cost-effective but has a unique lifting ability with endoscopic submucosal cushion and causes less tissue damage. This study aimed to evaluate the effectiveness and microscopic characteristics of a b...