Introduction. The etiology of male infertility characterized by non-obstructive azoospermia is largely unknown, especially at the molecular level. Identifying dysregulated microRNAs (miRNAs) in would be useful to achieve a more profound understanding its pathogenesis. Methods. Small RNA sequencing was performed on testicular tissues 10 nonobstructive azoospermic patients with Sertoli cell only ...

Abstract Study question Could the cell-free RNAs (cfRNAs) in seminal plasma be associated with male infertility and used as clinical biomarkers? Summary answer CfRNAs show different patterns men could serve diagnostic predictive factors infertility. What is known already Seminal a biological fluid containing large amounts of tissue-specific components secreted by organs reproductive system. Thu...

BACKGROUND Little is known about the extraction rate in repeated sperm retrieval procedures in azoospermic patients. This study aimed to assess the feasibility of repeated sperm recovery in these patients. METHODS A total of 1066 azoospermic men had their first sperm recovery between 1 January 1995 and 31 December 2003. A total of 381 men had obstructive azoospermia (OA), 628 nonobstructive a...

The manuscript on repeat microdissection testicular sperm extraction (microTESE) after prior failed microTESE for nonobstructive azoospermia (NOA) by Özman et al. (1Özman O. Tosun S. Bayazıt N. Cengiz Bakırcıoğlu M.E. Efficacy of the second micro-TESE first in men with azoospermia.Fertil Steril. 2021; 115: 915-921Scopus (5) Google Scholar) provides a simple message, and it also allows us some i...