Nonabsorbable antibiotics for selective bowel decontamination (SBD) sometimes are administered to liver transplant patients to prevent postoperative infections, but the efficacy of SBD is not known. Accordingly, we prospectively studied 69 patients randomly assigned to receive conventional prophylaxis with systemic antibiotics (control patients) or conventional prophylaxis plus oral nonabsorbab...

OBJECTIVES Providing patients with instructions and equipment regarding self-removal of nonabsorbable sutures could represent a new efficiency in emergency department (ED) practice. The primary outcome was to compare the proportion of patients successfully removing their own sutures when provided with suture removal instructions and equipment versus the standard advice and follow-up care. Secon...

Ion exchange resins (IER) are cross-linked, water insoluble polymers carrying ionizable functional groups on their repeating positions. They are considered as safe materials due to their insoluble and nonabsorbable nature. This advantage made IER subject of several research in different areas of pharmaceutical technology such as oral sustained release, taste masking, rapid dissolution, stabilit...

Recurrent, peptic ulcer following surgery has a 3% to 10% recurrence rate. Recurrence is due to one of the following causes: incomplete vagotomy, failure of gastric drainage, inadequate gastric resection, Zollinger-Ellison syndrome, hyperplasia of the antral gastric-secreting cells or due to use of nonabsorbable sutures. Lack of or incomplete vagotomy has been the most common cause. Gastric ulc...

Multiple ligament-injured knees are a heterogeneous group of knee injuries that lack a clear consensus on optimal treatment. Current areas of controversy include optimal timing of surgery, ligamentous repair vs reconstruction, and combined vs staged procedures. In addition, multiple open, arthroscopic, and arthroscopic-assisted techniques exist for repair and reconstruction of the injured stabi...

We conducted a two-part meta-analysis to assess the effectiveness of fluoroquinolones for preventing bacterial infections in granulocytopenic patients who are receiving chemotherapy for malignancies. Overall, 19 randomized studies met selection criteria and were included in this meta-analysis of 2,112 patients. Thirteen studies that compared the fluoroquinolones alone with control regimens (co-...

BACKGROUND Carbapenem-resistant Enterobacteriaceae (CRE) are emerging. In attempt to eradicate CRE colonization, we conducted a semirandomized, prospective, controlled trial using oral nonabsorbable antibiotics. METHODS Consecutive hospitalized CRE carriers were studied. Patients whose rectal isolates were gentamicin sensitive but colistin resistant were treated with gentamicin. Patients whos...

An in vitro method is presented which measures valid, unidirectional uptake rates for lipids across the intestinal brush border. This method combines analysis by a newly devised, double isotope counting system for solubilized tissue with the use of a nonabsorbable marker to correct gross uptake determinations for contamination by adherent mucosal fluid. Of seven markers, only [(3)H]inulin measu...

We report herein a technique for the repair of recurrent diaphragmatic hernia after repair of diaphragmatic rupture. Although chest roentgenography and computed tomography in a patient who presented with postprandial abdominal pain demonstrated a left intrathoracic intestinal shadow, the hernia was disregarded. To repair a diaphragmatic rupture along with intrathoracic adhesions, we performed a...

Selective beta 2-agonist aerosols may produce significant cardiovascular effects. In the present study we used Holter monitoring to compare the arrhythmogenic effects of inhaled terbutaline (TE), a beta 2-agonist, with that of ipratropium bromide (IB), a nonabsorbable cholinergic drug. Fourteen patients with concomitant obstructive lung disease, ischemic heart disease, and complaints of postinh...