BACKGROUND Infection or stimulation of the innate immune system by nonspecific microbial antigens is thought to educate the immune system to respond appropriately to allergens, preventing allergy. OBJECTIVE To determine the immunologic pathways that might explain how infection/microbial exposure inhibits allergic sensitization. METHODS Immunologic studies of non-antigen-specific functions o...

Non-hematopoietic lymph node stromal cells shape immunity by inducing MHC-I-dependent deletion of self-reactive CD8+ T cells and MHC-II-dependent anergy of CD4+ T cells. In this study, we show that MHC-II expression on lymph node stromal cells is additionally required for homeostatic maintenance of regulatory T cells (Tregs) and maintenance of immune quiescence. In the absence of MHC-II express...

background: chronic non-specific low back pain is a common disorder that often has no clear mechanism. exercise therapy is an effective and safe method for treatment of chronic musculoskeletal disorders such as back pain. pilate’s and williams’ exercises are two types of distinct exercises used for the treatment of back pain, but there is no evidence for the advantage of these two exercises in ...

objective: medical students are exposed to various infectious diseases during their clinical training period, including measles and rubella. in iran, to control the outbreaks of measles and rubella a mass vaccination campaign was conducted on 2003. the present investigation evaluates immunity to measles and rubella in a group of babol medical students and determines the prevalence of medical st...

Serum complement is valuable tool in determining the health status of fish. This study was conducted to examine in vitro activity of serum complement as an indicator of innate immunity in four sturgeon species, Acipenser stellatus, A. baeri, A. nudiventris and Huso huso (Chondrostei: Acipenseridae). The Effects of different temperatures, concentrations and volumes of serum on alternative comple...