نتایج جستجو برای: non alcoholic cirrhosis

تعداد نتایج: 1359109  

2011
D. S. Jayaprakash

Liver diseases are common disorders encountered in clinical practice. Investigations in Liver diseases are used to detect hepatic abnormality, to measure its severity, to define its structural effect on the liver to look for specific causes of Liver diseases to assess prognosis and to evaluate therapy. Aims and Objectives: To study and compare the altered serum levels of Alkaline phosphatase, B...

2006
A D BURT R S ANTHONY W S HISLOP R N M MACSWEEN

Using an indirect immunofluorescence technique liver membrane antibodies of IgG and IgA class have been demonstrated in a statistically significant proportion of sera from patients with alcoholic hepatitis and alcoholic cirrhosis. IgG and IgA class antibodies were found respectively in 23 and 25% of 48 patients with alcoholic hepatitis, in 27 and 33% of 84 with active cirrhosis, and 67 and 58% ...

Journal: :British medical journal 1981
J B Saunders J R Walters A P Davies A Paton

A total of 512 people from a defined population in west Birmingham served by a district general hospital were found to have cirrhosis in the period 1959-76. The annual incidence rose from 5.6 per 100 000 to a peak of 15.3 per 100 000 in 1974. This was due to an increase in the incidence of alcoholic cirrhosis, which in the last six years accounted for two-thirds of cases. The proportion of pati...

Journal: :Laboratory medicine 2016
Monika Gudowska Ewa Gruszewska Anatol Panasiuk Bogdan Cylwik Magdalena Świderska Robert Flisiak Maciej Szmitkowski Lech Chrostek

OBJECTIVE To evaluate the effectiveness of certain noninvasive liver-damage markers in predicting liver diseases and the clinical severity of liver cirrhosis. METHODS We tested serum specimens from 57 patients with alcoholic cirrhosis, 30 with nonalcoholic cirrhosis, and 22 with toxic hepatitis (TH). The Bonacini, King, and Göteborg University Cirrhosis Index (GUCI) scores were calculated usi...

Izadi, M., Sasani, M.R.,

Abstract Background and Objectives Non-alcoholic liver disease (NAFLD) is a spectrum of diseases, ranging from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH) which can lead to liver cirrhosis and hepatocellular carcinoma. Nonalchololic fatty liver  is the most prevalent hepatic disorder worldwide which can affect up to the one out of four adults. Little is known about...

2003
Takashi Tanaka Yoshio Hirota Maki Kuriyama Shuhei Nishiguchi Shuzo Otani

In Japan, preventive measures for hepatocellular carcinoma are urgently required, because the prevalence of this neoplasm and associated mortality have been increasing (Takada et al., 1994). It is clear that most non-viral cases of hepatocellular carcinoma arise with a background of alcoholic liver cirrhosis and that the incidence of hepatocellular carcinoma is higher in heavy drinkers than in ...

2015
Scott E. Hadland Ziming Xuan Jason G. Blanchette Timothy C. Heeren Monica H. Swahn Timothy S. Naimi

INTRODUCTION Stronger alcohol policies predict decreased alcohol consumption and binge drinking in the United States. We examined the relationship between the strength of states' alcohol policies and alcoholic cirrhosis mortality rates. METHODS We used the Alcohol Policy Scale (APS), a validated assessment of policies of the 50 US states and Washington DC, to quantify the efficacy and impleme...

2013
Hans Dieter Nischalke Cordula Berger Philipp Lutz Bettina Langhans Franziska Wolter Marianne Eisenhardt Benjamin Krämer Pavlos Kokordelis Andreas Glässner Tobias Müller Jonas Rosendahl Janett Fischer Thomas Berg Frank Grünhage Ludger Leifeld Michael Soyka Jacob Nattermann Tilman Sauerbruch Felix Stickel Ulrich Spengler

BACKGROUND AND AIMS CXCL1 (CXC chemokine-ligand-1) is a ligand for CXC chemokine receptor 2 expressed on hepatic stellate cells (HSC). Thus, CXCL1 might contribute to HSC activation and fibrogenesis. In the present study, we investigated the influence of the CXCL1 rs4074 polymorphism on the occurrence of alcohol induced liver cirrhosis and hepatocellular carcinoma (HCC). METHODS The study inv...

Journal: :Alcohol and alcoholism 2004
Luca Valenti Tullia De Feo Anna Ludovica Fracanzani Erika Fatta Mario Salvagnini Sarino Aricò Giorgio Rossi Gemino Fiorelli Silvia Fargion

AIMS To determine whether the functional A49G polymorphism of cytotoxic T-lymphocyte antigen-4 (CTLA-4), a T-cell surface molecule that modulates T-lymphocyte activation and influences the risk of developing alcohol-induced autoantibodies, plays a role in susceptibility to alcoholic liver disease (ALD) and influences disease severity in Italian alcohol abusers. METHODS One hundred and eighty-...

Journal: :JHEP reports 2023

Non-alcoholic fatty liver disease (NAFLD) is a major cause of worldwide, affecting up to 30% adults. Progression non-alcoholic steatohepatitis (NASH) key risk factor for cirrhosis, hepatocellular carcinoma and cardiovascular events. Alterations in reproductive hormones are linked the development and/or progression NAFLD/NASH women. Women with Polycystic Ovary Syndrome (PCOS) those estrogen defi...

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