Many medicinal plants have been reported to exhibit protective effects against many physiological diseases as a result of their phytochemical components which are effective antioxidants. This study was aimed at comparing the phenolic and flavonoids contents, antioxidant cytotoxic activities methanol extract Jatropha curcas seeds leaves. The cytotoxicity level J. assessed using brine shrimp leth...

Moringa oleifera is a common plant and known for various medicinal properties. The research work was conducted to investigate the in vitro antimicrobial and antioxidant activity of aqueous, ethanolic and methanolic extract of leaf Moringa oleifera. In-vitro antimicrobial activity was performed by disc diffusion method in MH agar medium and MIC test. The extract showed significant effect on the ...

We investigated whether niacin-related compounds had radical-scavenging activity by electron spin resonance methods. Many compounds, but not trigonelline, had radical-scavenging activity against hydroxyl radicals. However, for the nitric oxide radical and 1,1-diphenyl-2-picrylhydrazyl radical, only nicotinic acid hydrazide and isonicotinic acid hydrazide had scavenging activities. These results...

BACKGROUND Acacia hydaspica belongs to family leguminosae possess antioxidant, anti-inflammatory and anticancer activities. During our search for antioxidant compounds from A. hydaspica, we carried out bioassay guided fractionation and obtained antioxidant compounds with free radical scavenging activity. MATERIALS AND METHODS The polyphenol compounds in the plant extract of A. hydaspica were ...

BACKGROUND Macrofungi have an established history of use in traditional oriental medicine. Anthracophyllum lateritium is a terrestrial macrofungus found in the dry zone forest reserves in Sri Lanka. Yet there are no scientific reports on bioactive properties of this species. Hence, the current study was aimed at determining the antioxidant potential, in vitro antiproliferative activity and apop...

In the present study, the antioxidant activity of the polysaccharides from aloe vera (Aloe barbadensis Miller) gel was evaluated, in vitro by five established methods, 1,1-diphenyl-2-picrylhydrazyl (DPPH(-)) radical scavenging, nitric oxide (NO) scavenging, hydrogen peroxide scavenging, superoxide radical (O(-2)) scavenging and reducing power assay, and in vivo against doxorubicin (DOX)-induced...

Under normal physiological conditions activation of nitric oxide synthases produces both nitric oxide and superoxide in equimolar concentrations (Figure 1). We propose a hypothesis that in hypoxia-reoxygenation injury this balanced co-production of nitric oxide and superoxide is disturbed and results in pathological effects. Specifically, under hypoxic conditions nitric oxide synthase is activa...

Tetramethylpyrazine is one of the active ingredients of the Chinese herb Ligusticum wallichii Franchat. By electron spin resonance spin trapping methods, effects of tetramethylpyrazine on superoxide anion and nitric oxide generated by human polymorphonuclear leukocytes were studied. During the respiratory burst of polymorphonuclear leukocytes induced by N-formylmethionyl-leucyl-phenylalanine, t...

In vitro antioxidant activities of methanolic extract of tuberous root of coleous vettiveroides (jacob.) was investigated. The free radical scavenging activity to evaluate by DPPH (2,2 -diphenyl -1picryl hydrazyl) method, Nitric oxide method, Total antioxidant activity. DPPH radical scavenging activity of Methanolic extract and reference standard Rutin IC50 values was found to be 250 μg/ml and ...