نتایج جستجو برای: nitazoxanide

تعداد نتایج: 375  

Journal: :Biocell 2022

Osteoporosis is a frequently occurring bone remodeling disorder worldwide with one characteristic being decreasing mineral density and predisposition to fracture, which diminishes patients’ quality of life. Several studies showed that imbalance between the osteogenesis adipogenesis marrow mesenchymal stem cells (BMSCs) took part in development osteoporosis. In previous study, we found MIR22HG r...

2015
B. D. Sahu S. K. Maiti

The present study was undertaken to assess the therapeutic efficacy of oral Nitaxoxanide and Sulphadimidine treatment against Cryptosporidium infection in bovine calves reared under field conditions. A total of 18 diarrhoeic calves naturally infected with Cryptosporidium infection were evaluated. Nitazoxanide was found to be very effective on the basis of disappearance of clinical signs, restor...

2017
Lauren M. Watson Elizabeth Bamber Ricardo Parolin Schnekenberg Jonathan Williams Conceição Bettencourt Jennifer Lickiss Katherine Fawcett Samuel Clokie Yvonne Wallis Penny Clouston David Sims Henry Houlden Esther B.E. Becker Andrea H. Németh

The metabotropic glutamate receptor 1 (mGluR1) is abundantly expressed in the mammalian central nervous system, where it regulates intracellular calcium homeostasis in response to excitatory signaling. Here, we describe heterozygous dominant mutations in GRM1, which encodes mGluR1, that are associated with distinct disease phenotypes: gain-of-function missense mutations, linked in two different...

2014
Peter J. Hotez

In 2011, the World Health Organization (WHO) determined that more than 700 million people were treated with at least one essential medicine for neglected tropical diseases (NTDs) under the auspices of a global preventive chemotherapy initiative [1,2]. However, a total of at least 1.9 billion people require annual preventive chemotherapy [1,2], so these efforts will need to be greatly expanded i...

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