This paper aims to propose a social protection system that "decommodifies" labour and fulfills the properties of a Social Protection Floor satisfying revenue-neutrality. To this end, firstly, a Universal Basic Income (UBI) scheme is explored. Secondly, the UBI is transformed into a Negative Income Tax (NIT) scheme, providing universal protection instead of universal benefits. Finally, the NIT i...

Type 1 diabetes is characterized by the autoimmune destruction of pancreatic β-cells. Recognition of major histocompatibility complex (MHC)-bound peptides is critical for both the initiation and progression of disease. In this study, MHC peptide complexes were purified from NIT-1 β-cells, interferon-γ (IFN-γ)-treated NIT-1 cells, splenic and thymic tissue of 12-week-old NOD mice, and peptides i...

OBJECTIVE To investigate whether a single nucleotide polymorphism (SNP) in the mitochondrial gene for NADH dehydrogenase 2 (mt-Nd2) can modulate susceptibility to type 1 diabetes in NOD mice. RESEARCH DESIGN AND METHODS NOD/ShiLtJ mice conplastic for the alloxan resistant (ALR)/Lt-derived mt-Nd2(a) allele (NOD.mt(ALR)) were created and compared with standard NOD (carrying the mt-Nd2(c) allele...

The aim of this in vitro study was to compare the sealing quality of three root canal filling materials after four years of ageing. Obturation with the non-instrumentation technique (NIT) was compared with cold lateral condensation of gutta-percha. Seventy-six canals were endodontically treated with traditional hand instrumentation and cold lateral condensation (control) whereas 77 canals were ...

IDDM results from pancreatic beta cell destruction by islet-reactive T cells, a process that involves beta cell apoptosis. Fas-FasL pathway plays a major role in pancreatic beta cell death. Fas-associated death domain protein (FADD), the component of the tumor necrosis factor receptor type 1 (TNFR1) and Fas signaling complexes, is involved in TNFR1- and Fas-induced apoptosis. Inhibiting the fun...

BACKGROUND The impact of diabetes mellitus on the clinical presentation and noninvasive test (NIT) results among stable outpatients presenting with symptoms suggestive of coronary artery disease (CAD) has not been well described. METHODS AND RESULTS The PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) trial enrolled 10 003 patients with known diabetic status, of wh...

Infusions of donor peripheral blood T cells can induce durable remissions of Epstein-Barr virus (EBV) lymphomas complicating marrow grafts, but they contain alloreactive T cells capable of inducing graft-versus-host disease. EBV-specific T-cell lines or clones avoid this problem but require 30 to 40 days of culture to establish. To accelerate the generation of EBV-specific T cells, we tested wh...

Neutral-ionic transitions (NITs) occur in organic charge-transfer (CT) crystals of planar π-electron donors (D) and acceptors (A) that form mixed stacks . . . D+ρA−ρD+ρA−ρD+ρA−ρ . . . with variable ionicity 0 < ρ < 1 and electron transfer t along the stack. The microscopic NIT model presented here combines a modified Hubbard model for strongly correlated electrons delocalized along the stack wi...

Reduction in enteric methane (CH4) emissions from cattle can be achieved through use of feed additives, which often results increased emission hydrogen (H2). The objective this study was to investigate vitro effects a known sink, fumaric acid, combination with either 2 inhibitors, the macroalga Asparagopsis taxiformis or nitrate, on CH4 and H2 production, degradability, pH, redox potential. A c...

Abstract We compare two welfare programs: the universal basic income (UBI) and negative tax (NIT). Under a linear system, we show that (i) NIT can replicate allocation of UBI exactly by providing an identical marginal effective schedule, (ii) budget is always smaller than UBI. According to our quantitative model, which calibrated approximate wealth distributions in United States, optimal pay ev...