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introduction mycobacterium tuberculosis (mtb) is one of the most common causes of disseminated granulomatous diseases especially in developing countries. case presentation we present a patient who had an unusual type of tuberculosis who was misdiagnosed with some other common diseases such as infective endocarditis and collagen vascular diseases. pathological examination helped us to make decis...

Pseudotumor cerebri is an uncommon manifestation of neuropsychiatric systemic lupus erythematosus (SLE), and is characterized by an elevated intracranial pressure, papilledema with occasional abducens nerve paresis, absence of a space-occupying lesion or ventricular enlargement, and normal cerebrospinal fluid chemical and hematological constituents. Pseudotumor cerebri has been reported in a fe...

macrophage activating syndrome (mas) is a life-threatening disease seen in autoimmune diseases including lupus erythematosus, rheumatoid arthritis, still's disease, polyarteritis nodosa. it is characterized by fever, pancytopenia, liver failure, coagulopathy, and neurologic symptoms and high serum ferritin. a 27 yr. old female patient was admitted in shahid mostafa khomeini hospital (tehra...

background: antiphospholipid antibody syndrome (aps) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (sle). anticardiolipin antibody (acl) of igg and/or igm isotype in blood, measured by a standardized elisa is the most acceptable laboratory criteria. aps igg isotype, particularly igg2 subclass is more strongly associated ...

results our study showed that there were no statistically significant differences in the allele and genotype frequencies of -1661 a/g snp between patients with sle and healthy controls (p > 0.05). conclusions in conclusion, we found no association between snp-1661 a/g of the ctla-4 promoter region and susceptibility to sle in our population. objectives to evaluate the potential influences of co...

conclusions the results of this study show that patients with sle have poorer hrqol in physical components whereas the mental component of qol is relatively similar to healthy individuals. depression and anxiety were not related to clinical manifestations of sle. however, the sf domain of hrqol was the most susceptible component of qol, which was affected by sle clinical variables. the high est...

BACKGROUND/OBJECTIVE Posterior reversible encephalopathy syndrome (PRES) is an underrecognized and reversible condition in systemic lupus erythematosus (SLE) that could mimic neuropsychiatric lupus. Identification of any distinct clinical patterns is important as one would need to escalate rather than decrease or discontinue immune suppression in neuropsychiatric lupus. METHODS We retrospecti...

SUMMARY During the course of systemic lupus erythematosus in a 10 year-old girl, a go it er develo ped. Subc linical I ly pothyrnic.Jism was found, in addition rising titer of ant imicrosomal antibody and overt hypothyroidism after 6-week cessation of thyroxin tablet lead to the diagnosis of Hashimoto's thyroiditis. Antibodies directed to the thyroid may result in an autoimmune thyroiditis in...