Neurological diseases are defined as an inappropriate function of the peripheral or central nervous system due to impaired electrical impulses throughout the brain and/or nervous system that may present with heterogeneous symptoms according to the parts of the system involved in these pathologic processes. Growing evidence on genetic components of neurological disease have been collected during...

this paper reviews the current literature examining the pervasive symptom of fatigue experienced in three of the most common degenerative neurological conditions: multiple sclerosis (ms), parkinson’s disease (pd) and post-polio syndrome (pps). the existing literature can be considered under four headings definition and prevalence, type, cause, impact of fatigue. fatigue is a common symptom in d...

Inflammation is an important factor in the pathophysiology of neurological diseases and the physiological response of the immune system against internal and external harmful stimuli. Inflammation is the natural response of the body to damage, which leads to the removal of debris from dead cells and infections from damage and tissue repair. In this study, neuropathic inflammation and its role in...

1 Modulation of iTBS effects applied over primary motor cortex 2 (M1) by conditioning stimulation of the opposite M1 3 4 5 Patrick Ragert1,2, Mickael Camus1, Yves Vandermeeren1,3, Michael A. Dimyan1, 6 Leonardo G. Cohen 7 8 1 Human Cortical Physiology and Stroke Neurorehabilitation Section (HCPS), 9 National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of 10 Healt...

Basic science studies demonstrated mechanisms of plasticity and metaplasticity. More recent human studies identified some of these mechanisms as operating in multiple areas of human cognition, such as learning and memory, and in functional recovery from lesions in the CNS, as in stroke. One of the goals of neurorehabilitation is the translation of these principles into rational strategies to pr...

We present the neurological complications evaluated in a series of 1000 patients who underwent hematopoietic stem cell transplantation (HSCT). Central nervous system (CNS) neurological complications, particularly brain hemorrhages, were the most common, followed by seizures and CNS infections. An unusual neurological complication was Wernicke's encephalopathy. Less frequent neurological complic...

Breathing is controlled by complex interactions between the central and peripheral nervous systems in conjunction with respiratory system. Neurological diseases predispose patients to nocturnal desaturation pneumonia due dysfunction, which increases mortality, daytime sleepiness fatigue, reduces quality of life. Respiratory function tests are required identify decline consider compensatory mana...

In some fields, Big Data has been instrumental in analyzing, predicting, and influencing human behavior. However, Big Data approaches have so far been less central in speech-language pathology. This article introduces the concept of Big Data and provides examples of Big Data initiatives pertaining to adult neurorehabilitation. It also discusses the potential theoretical and clinical contributio...