SME Sido Luhur is a producer that processes raw coffee beans who have problems ordering every month which considered to result in higher inventory costs. The sample this study were owner determined based on judgment sampling. research was conducted at starting September 2022. This used primary data obtained through interviews and secondary from the cost quantity of materials 2018. Data for 2018...

This study is the first to consider a distribution-free approach in newsvendor model with transfer of risk and back-ordering. Previously, many articles, discrete demand considered. In this model, we selling single seasonal item price-dependent stochastic demand. Competition markets has forced retailer manufacturer coordinate decentralized supply chain management. A coordination contract made be...

The Internet has radically reduced the cost of collecting and distributing information. Consequently, researchers initially predicted that the resulting price transparency would drive prices toward a single market price. However, this has largely not happened, partly because retailers use shipping costs to make prices less comparable. Using data on 517,048 offers of 895 retailers from a leading...

OBJECTIVE To evaluate the economic impact of the routine US childhood immunization schedule: diphtheria and tetanus toxoids and acellular pertussis; tetanus and diphtheria toxoids; Haemophilus influenzae type b conjugate; inactivated poliovirus; measles, mumps, and rubella; hepatitis B; and varicella vaccines. DESIGN Decision tree-based analysis was conducted using population-based vaccinatio...

Heparinase I from flavobacterium heparinum has several potential clinical applications; the resulting high demands on protein purity and quantity can be met by recombinant expression in Escherichia coli. Based on laboratory scale experiments with insoluble heparinase I expression followed by renaturation, a process for production of 3 kg/year of heparinase I was designed. We present a comparati...

OBJECTIVE To summarise how costs and health benefits will change with the adoption of total laparoscopic hysterectomy compared to total abdominal hysterectomy for the treatment of early stage endometrial cancer. DESIGN Cost-effectiveness modelling using the information from a randomised controlled trial. PARTICIPANTS Two hypothetical modelled cohorts of 1000 individuals undergoing total lap...

Aims. To investigate the costs and cost-effectiveness of a short message service (SMS) intervention to prevent the onset of type 2 diabetes mellitus (T2DM) in subjects with impaired glucose tolerance (IGT). Methods. A Markov model was developed to simulate the cost and effectiveness outcomes of the SMS intervention and usual clinical practice from the health provider's perspective. The direct p...

OBJECTIVE To analyse the economic benefits, in comparison with placebo, of the secondary prevention of ischaemic stroke and myocardial infarction (MI) with lysine acetylsalicylate (Kardégic) in patients with a history of ischaemic stroke, MI or stable and unstable angina pectoris. DESIGN AND SETTING This was a modelling study from the perspectives of direct medical costs, the social security ...

OBJECTIVES To evaluate potential return on investment of the National Health Service Diabetes Prevention Programme (NHS DPP) in England and estimate which population subgroups are likely to benefit most in terms of cost-effectiveness, cost-savings and health benefits. DESIGN Economic analysis using the School for Public Health Research Diabetes Prevention Model. SETTING England 2015-2016. ...