After spinal cord injury (SCI), external urethral sphincter (EUS) hyperreflexia often develops which can lead to an inability to properly empty the bladder. Short of catheterization and irreversible surgery, few options exist for managing this condition. High-frequency electrical stimulation can produce a reversible block of peripheral nerve conduction, and has been proposed as a way to block u...

The effects of regional intravenous analgesia in the upper limb were studied in eight subjects by means of clinical examination and serial nerve conduction techniques. The changes following 1 per cent lignocaine analgesia and ischaemia were compared with those following ischaemia alone; the latter produced analgesia and impairment of conduction at a considerably slower rate than it did when com...

The refractory period, the ability to transmit trains of impulses, and the effect of temperature on conduction, have been studied in the sciatic-tibial nerve trunks of Trembler mice, which suffer from a dominantly inherited hypertrophic neuropathy. Both the refractory period of transmission and the relative refractory period were increased in Trembler mice when compared with controls. The nerve...

Nerve conduction studies are an essential part of the work-up of peripheral neuropathies. Many neuropathic syndromes can be suspected on clinical grounds, but optimal use of nerve conduction study techniques (in combination with needle electromyography) allows diagnostic classification and is therefore crucial to understanding and separation of neuropathies. Multifocal motor neuropathy, for exa...

background: the pneumatic tourniquet (pt) is routinely used in upper and lower limb operations by most orthopaedic surgeons. the silicone ring tourniquet (srt) was introduced in clinical practice the last decade. clinical as well comparative studies in volunteers concerning its safety and efficacy have been published. the aim of this study was to investigate the postoperative effect of the sili...

Neuromodulation therapies, which electrically stimulate parts of the nervous system, have traditionally attempted to activate neurons or axons to restore function or alleviate disease symptoms. In stark contrast to this approach is inhibiting neural activity to relieve disease symptoms and/or restore homeostasis. One potential approach is kilohertz electrical stimulation (KES) of peripheral ner...

The degeneration-regeneration process induced by bupivacaine injection has been studied in rat extensor digitorum longus (EDL) muscle in the presence or absence of nerve, the presence of tetrodotoxin (TTX)-induced block of nerve impulse conduction, and the presence of vinblastine-induced block of nerve axoplasmic flow associated to TTX block. Seven and 14 days after bupivacaine injection, myosi...

Endoscopic radial artery harvesting (ERAH) is a feasible and attractive minimally invasive approach for conduit procurement, however there have been concerns about a potential neurological damage occurring at the harvest limb site secondary to injury of the radial nerve during endoscopic harvesting. We present a case of ERAH in which we evaluated intraoperatively the characteristics of radial n...

To explore suggestive evidence of focal proximal demyelination in multifocal motor neuropathy (MMN) without overt evidence of conduction block, we conducted sonographical assessment of cervical nerve roots in 9 MMN patients, 22 ALS patients, and 17 control subjects. The mean diameters of the C5 and C6 roots in MMN patients were significantly larger than those in ALS and controls, especially on ...

Carpal tunnel syndrome (CTS) is the most well-known and frequent form of median nerve entrapment, and accounts for 90% of all entrapment neuropathies. Entrapment neuropathies of the ulnar nerve are relatively common with ulnar neuropathy at the elbow more prevalent than ulnar neuropathy at the wrist. The diagnosis of ulnar neuropathy at the elbow is usually confirmed in a relatively straight – ...