نتایج جستجو برای: neoplastic cell lines

تعداد نتایج: 1805913  

Journal: :Neuro-oncology 2022

Abstract CAR-T cell therapy is a promising new immunotherapy for number of difficult-to-treat cancers, however, it has yet to yield broad success in glioblastoma (GBM). In particular, tumor heterogeneity presents major therapeutic challenge, and detailed understanding the complex interplay between different neoplastic, non-neoplastic, cells critical developing better treatments. Using patient-d...

2006
R. W. Trewyn Sylvia J. Kerr

Primary Chinese hamster embryo cell cultures generally yield cell lines with a finite lifetime in culture. However, if early-passage cells are exposed chronically to either of two normal degradation products of transfer RNA, 1-methylguanine or 7-methylguanine, they are converted to con tinuous lines with altered growth characteristics and mor phology. The continuous cell lines have saturation d...

Journal: :Cancer research 1978
R W Trewyn S J Kerr

Primary Chinese hamster embryo cell cultures generally yield cell lines with a finite lifetime in culture. However, if early-passage cells are exposed chronically to either of two normal degradation products of transfer RNA, 1-methylguanine or 7-methylguanine, they are converted to continuous lines with altered growth characteristics and morphology. The continuous cell lines have saturation den...

Journal: :iranian journal of basic medical sciences 0
ebrahim faghihloo department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, iran abolfazl akbari colorectal research center, iran university of medical sciences, tehran, iran fatemeh adjaminezhad-fard department of virology, school of public health, tehran university of medical sciences, tehran, iran talat mokhtari-azad department of virology, school of public health, tehran university of medical sciences, tehran, iran

objective(s): valproic acid (vpa) has proven to be as one of the most promising useful drug with anticancer properties.in this study, we investigate the vpa effects on e-cadherin expression in hela, tc1, mkn45, and hct116 cell lines.  this study assesses the effects of vpa on human papillomavirus e7 expression in hpv positive cell lines. materials and methods: cell lines were treated by2 mmol/l...

2013
Danielle Queiroz Calcagno Vanessa Morais Freitas Mariana Ferreira Leal Carolina Rosal Teixeira de Souza Samia Demachki Raquel Montenegro Paulo Pimentel Assumpção André Salim Khayat Marília de Arruda Cardoso Smith Andrea Kely Campos Ribeiro dos Santos Rommel Rodriguez Burbano

BACKGROUND MYC deregulation is a common event in gastric carcinogenesis, usually as a consequence of gene amplification, chromosomal translocations, or posttranslational mechanisms. FBXW7 is a p53-controlled tumor-suppressor that plays a role in the regulation of cell cycle exit and reentry via MYC degradation. METHODS We evaluated MYC, FBXW7, and TP53 copy number, mRNA levels, and protein ex...

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