In the newborn period, unconjugated hyperbilirubinemia (UHB) is common, multifactoral, and associated with a variety of physiologic and pathologic conditions. The most commonly identified pathologic cause leading to hyperbilirubinemia is hemolytic disease of the newborn. We report a five-days-old female infant with neonatal jaundice secondary to splenic hematoma.

Normal full-term infants may have transient unconjugated hyperbilirubinemia that rarely exceeds 5 mg per 100 ml during the first 3 to 5 days of life (1, 2). This so-called physiologic hyperbilirubinemia is believed to result from delayed development of the hepatic glucuronide conjugating system (3-5), particularly glucuronyl transferase (6). Numerous factors, such as hemolysis, infection, drugs...

BACKGROUND Prediction of severe neonatal hyperbilirubinemia is very important for early treatment and prophylaxis of neurologic sequels. The aim of this study was to evaluate the predictive role of umbilical cord -fetoprotein (UCAFP) as a marker of an increased risk for neonatal hyperbilirubinemia in full term babies. METHODS Umbilical cord blood was collected from 400 term singleton full ter...

Background: Prediction of severe neonatal hyperbilirubinemia is very important for early treatment and prophylaxis of neurologic sequels. The aim of this study was to evaluate the predictive role of umbilical cord ^5-fetoprotein (UCAFP) as a marker of an increased risk for neonatal hyperbilirubinemia in full term babies. Methods: Umbilical cord blood was collected from 400 term singleton full t...

UNLABELLED With the universal hearing screening we can prevent auditory disorders in children. AIM To characterize the program of neonatal auditory screening into a population of neonates. MATERIALS AND METHODS longitudinal cohort study. We surveyed the clinic's database on neonatal auditory screening in the city of Porto Velho, Rondônia. RESULTS Among the 6,889 newborns in the database, ...

BACKGROUND Blood group mismatch between a mother and newborn carries a substantial risk for neonatal hyperbilirubinemia and kernicterus. In the current study, we investigate the spectrum and outcome of marked neonatal hyperbilirubinemia with blood group incompatibility. METHODS We retrospectively assessed a cohort of 413 neonates with peak total serum bilirubin (TSB) values > or = 20 mg/dL be...

BACKGROUND Neonatal hyperbilirubinemia is a common clinical manifestation of the inherited glucose-6-phosphate dehydrogenase (G6PD) deficiency. AIM OF THE STUDY The aim of this study was to investigate the influence of the inherited G6PD deficiency on the appearance of neonatal hyperbilirubinemia in southern Croatia. METHODS The fluorescent spot test (FST) was used in a retrospective study ...

Neonatal jaundice is seen in up to 60% of full-term infants and 80% of preterm infants during the first week of life. While it is often considered as a single clinical entity, neonatal jaundice is a physical finding associated with many possible etiologies. Jaundice is observed when the pigment bilirubin accumulates in the skin, sclera and other tissues. The importance of correctly identifying ...