herpes simplex virus (hsv) is one of the common pathogenic viruses of humans bing. this study aimed to determin anti-herpes virus activity of mentha piperita extracts in vitro. mentha piperita extracts can inhibit hsv infection when the cells treated before viral adsorbtion. hsv-1 were also inhibited by menthol after viral adsorption. hsv-1 viral particles were directly inhibited and viral yiel...

We describe a case of a severe neonatal infection by herpes simplex virus (HSV) type 1 acquired postnatally from his father. The delivery and the first days of life were normal. He developed liver failure and disseminated intravascular coagulation when he was 19 days old. He was treated with intravenous acyclovir and the outcome was favorable. This case underlines that prevention of post-natal ...

Background: Herpes simplex viruses (HSV) are human pathogens that establish lytic and latent infections. Reactivation from latency occurs intermittently, which represents a life-long source for recurrent infection. The role of immune factors in the control of recurrent symptomatic HSV lesions is complex and the exact role of cytokines remains unclear. Objective: To assess the levels of tumor ne...

Neonatal pneumonia diagnosed in 0.5 1.0% of full-term and 10 15% of premature babies. Of neonatal pneumonia contributes to failure resulting from maternal immunity factors, which affects the function of the immune system and, in particular, the mechanisms of innate immunity. Lactoferrin one of the factors of innate immunity directed against a range of bacteria, viruses and fungi. The aim of the...

Neonatal herpes simplex virus (HSV) infection produces severe disease with unacceptable morbidity and mortality with current antiviral therapies. The effect of therapy with passive anti-HSV antibody and acyclovir was evaluated using a guinea pig model of neonatal HSV. Newborn animals were inoculated intranasally and treated with acyclovir (60 mg/kg/day) or antibody (or both), beginning on days ...

Neonatal Herpes Simplex Virus (HSV) infection is a serious illness with significant mortality and morbidity for disseminated disease. Clinical diagnosis of neonatal HSV infection is often difficult without evidence of HSV exposure, for example, absence of a rash or the presence of non-specified manifestations in an infant. Early recognition and treatment with high-dose Acyclovir may dramaticall...

Many cases of acute retinal necrosis caused by HSV-2 have been reported in children, teenagers, and young adults as a result of reactivation of congenital or neonatal infections, which may have been subclinical. Pediatricians should be aware of this entity and alert to recurrences that may be delayed by years.

Lymphocytes from individuals with laboratory evidence of prior infection with herpes simplex virus (HSV) type 1 or type 2 demonstrated transformation (av antigens. Higher stimulation indexes were obtained when lymphocytes were incubated with the homologous as compared with the heterologous antigen. Higher mean lymphocyte stimulation indexes were also demonstrated in seropositive as compared wit...

Five cases of fatal generalized herpes simplex infection in malnourished children are described. This is almost certainly a much more common disease in underdeveloped communities than is at present appreciated. Only a greater awareness of the disease, coupled with full use of histological and cultural methods of diagnosis, will lead to knowledge of its true frequency.A case of neonatal infectio...