The Dutch-Belgian Randomized Lung Cancer Screening Trial (Dutch acronym: NELSON study) was designed to investigate whether screening for lung cancer by low-dose multidetector computed tomography (CT) in high-risk subjects will lead to a decrease in 10-year lung cancer mortality of at least 25% compared with a control group without screening. Since the start of the NELSON study in 2003, 7557 par...

49 contributors the book has been completely rewritten and embraces a wide field of the subject ranging from the care of the unborn child to the supervision of the adolescent, and from the infant feeding to the management of behaviour disorders. Subjects like physical, mental and emotional development, the part played by heredity, nutritional requirements and feeding of children, formation of h...

discussion of the many faces of relativism occupies a highly prominent place in the epistemological literature. protagoras in ancient greece and nelson goodman in the modern period are two most notable proponent of relativism. in the present article, i discuss and explain relativistic approaches of this two important relativist. i will first briefly define and review some faces of relativism. t...

We prove that if a real-valued function of the plane sums to zero on the four vertices of every unit square, then it must be the zero function. This fact implies a lower bound in a “coloring of the plane” problem similar to the famous Hadwiger–Nelson problem, which asks for the smallest number of colors needed to assign every point in the plane a color so that no two points of unit distance apa...

In previous papers (J. Combin Theory Ser. A 103 (2003) 387) and (J. Combin. Theory Ser. A 105 (2004) 359) Saharon Shelah and I formulated a conditional chromatic number theorem, which described a setting in which the chromatic number of the plane takes on two different values depending upon the axioms for set theory.We also constructed examples of a distance graph on the real line R and differe...

The chromatic number of a subset of the real plane is the smallest number of colors assigned to the elements of that set such that no two points at distance 1 receive the same color. It is known that the chromatic number of the plane is between 4 and 7. In this note, we determine the bounds on the chromatic number for several classes of subsets of the plane such as extensions of the rational pl...

The potential role of physical correlates of articulatory variability in vowel production was studied by means of EMMA and EPG. In accordance with Perkell & Nelson (1985), the hypothesis to be tested is that the amount and shape of token-totoken variability is influenced by the amount of palatal contact in such a way that high vowels exhibit different variability patterns than the other vowels....

Adam D. Feenstra, Liza E. Alexander, Zhihong Song, Andrew R. Korte, Marna D. Yandeau-Nelson, Basil J. Nikolau, and Young Jin Lee Department of Chemistry, Iowa State University, Ames, Iowa 50011 Ames Laboratory-United States Department of Energy, Ames, Iowa 50011 Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011 Center for Metabo...

In survival analysis, estimates of median survival times in homogeneous samples are often based on the Kaplan-Meier estimator of the survivor function. Confidence intervals for quantiles, such as median survival, are typically constructed via large sample theory or the bootstrap. The former has suspect accuracy for small sample sizes under moderate censoring and the latter is computationally in...