BACKGROUND A common functional polymorphism, 5-HTTLPR, in the serotonin transporter gene has been associated with heavy drinking in college students. We examined this polymorphism as it interacted with negative life events to predict drinking and drug use in college students. METHODS Daily reports of drinking and drug use obtained using a daily web-based survey were combined with self-reports...

The authors tested neighborhood context, negative life events, and negative affectivity as predictors of the onset of major depression among 720 African American women. Neighborhood-level economic disadvantage (e.g., percentage of residents below the poverty line) and social disorder (e.g., delinquency, drug use) predicted the onset of major depression when controlling for individual-level demo...

In a two-phase study, we examined the relations of subjective well-being with the cognitive processing of affectively valenced life events. In Phase 1, both more intense and more enduring reactions to positive life events than negative ones were associated with higher well-being, and for intensity of reactions, this relation was stronger for those events that were subsequently recalled. When eq...

This study examined the relationship of attributional styles for negative and positive events with depression and anxiety. A sample of 239 college students underwent structured diagnostic interviews and completed self–report measures of attributional style and major life events at two time points separated by approximately four weeks. Using cross–sectional methodology, attributional styles for ...

Background and Aims: Identifying risk factors for incidence of migraine headaches through an integrated model of psychosocial factors is important. This research aimed to investigate the predictive role of psychological, socioeconomic and lifestyle-related factorsin migraine headaches. Methods: In a cross-sectional descriptive study, 71 patients with migraine headaches who referred to Imam ...

OBJECTIVES The purpose of this study was to assess the relationship between apolipoprotein E (APOE), life events and engagement, and subjective well-being (as measured by positive and negative affect) among centenarians. Based on the life stress paradigm, we predicted that higher levels of stress would allow APOE to influence positive and negative affect. METHOD 196 centenarians and near-cent...