Necrobiosis lipoidica (NL) is a cutaneous disease entity that typically manifests as atrophic yellow plaques with telangiectasias on the anterior tibial region. Although NL is commonly associated with diabetes mellitus, the role of trauma in disease development is less commonly emphasized. The relationship between NL and the Köbner phenomenon has been established, as a few cases of NL occurring...

Necrobiosis lipoidica is a rare chronic granulomatous disease, often associated with diabetes mellitus. It due to collagen degeneration risk of ulceration. affects 0.3 1.2% diabetic patients, mainly in the leg. Its etiology not yet well understood. The diagnosis usually made clinically but skin biopsy may be necessary case atypical lesions. evolution ulceration and into squamous cell carcinoma ...

We present a case of necrobiosis lipoidica (NL) with atypical early lesions and good response to topical tacrolimus. NL is a disease with clinical features that are seldom misinterpreted. Often histology just confirms the clinician's diagnosis. Only in rare cases, the clinical presentation and the involved body sites may be misleading. A 67-year-old diabetic woman was admitted to our department...