Suggested citation: Ribeiro JD. Aerosols and spacers for acute asthma in children. Evolution and time to change the routine. J Pediatr (Rio J). 2005;81:274-6. Several studies have shown that valved (metal or plastic) spacers and, even homemade spacers (made out of bottles and plastic cups), are equivalent to or more advantageous than nebulizers for the delivery of medication in acute asthma att...

The Agilent OneNeb nebulizer is a novel nebulizer design that offers superior performance compared to other commercially available concentric nebulizers used with ICP-OES instruments. This universal nebulizer provides improved sensitivity, greater tolerance to dissolved salts, and is inert so it is suitable for use with strong acids such as hydrofl uoric acid (HF) and most common organic solven...

We have developed a conceptual and mathematical model for nebulizer performance that attempts to provide a unifying theoretical framework for subsequent in vitro studies. Specifically, we have created a lexicon and a way to describe the effects of a standardized breathing pattern for evaluating small-volume jet nebulizers. This model should help researchers communicate more clearly and study pl...

Inhalation product development is an important area of activity for the pharmaceutical sector. Asthma and chronic obstructive pulmonary disease (COPD) are becoming increasingly common and there is growing recognition of the benefits of the pulmonary route for systemic drug delivery. The industry is responding by investing heavily in both formulation and device research. Inhalation delivery plat...

Nebuliser drug delivery units were reused in 15% of paediatric wards participating in a national survey, while routine servicing and written information was provided by only half the wards issuing home nebulisers. Written information should be developed as a national resource, and further research on optimal cleaning practices is required.