PURPOSE This work is a preliminary study of a stationary cardiac SPECT system. The goal of this research is to propose a stationary cardiac SPECT system using segmented slant-hole collimators and to perform computer simulations to test the feasibility. Compared to the rotational SPECT, a stationary system has a benefit of acquiring temporally consistent projections. The most challenging issue i...

The interest of PET complementary information for the delineation of the target volume in radiotherapy of lung cancer is increasing. However, respiratory motion requires the determination of a functional internal target volume (ITV) on PET images for which several strategies have been proposed. The purpose of this study was the comparison of these strategies for taking into account respiratory ...

Introduction: We have investigated cardiac SPECT with slant hole collimator in which the holes are slanted towards the target organ, to provide greater sensitivity over the parallel hole collimator. In addition, parallel hole collimator was used to obtain a comparison in FWHM, sensitivity, Compton and photoelectric area values in the simulations. Materials and Methods...

The x-ray imaging dose from serial cone-beam computed tomography (CBCT) scans raises a clinical concern in most image-guided radiation therapy procedures. It is the goal of this paper to develop a fast graphic processing unit (GPU)-based algorithm to reconstruct high-quality CBCT images from undersampled and noisy projection data so as to lower the imaging dose. For this purpose, we have develo...

Quantitative description of cardiac motion is desirable to assist in detecting myocardial abnormalities from gated myocardial perfusion (GMP) emission computed tomography (ECT) images. While "optical flow" type of cardiac motion estimation (ME) techniques have been developed in the past, there has been no quantitative evaluation of their performance. Moreover, no investigation has been performe...

Gated cardiac SPECT imaging has been widely used in the evaluation of cardiac functions. The acquired fourdimensional (4D) sinogram data have both inter-frame correlation among the time sequence and intra-frame correlation within each 3D frame. The unique features of Karhune-Loève (KL) transform for de-correlating the data sequence for noise reduction, feature extraction, etc, have been well re...

Introduction: To investigate the effects of breathing cycle and tree diaphragm motions on prostate cancer tumors standard uptake value (SUV) during positron emission tomography (PET) and to correct it. Materials and methods: Respiratory motion traces were simulated on the common patient breathing cycle and tree diaphragm motio...