The theme of this year’s annual meeting of the European Academy of Childhood Disability (EACD) is ‘Treatment of Childhood Disabilities’. The meeting in Pisa (24–26 October) will examine, through lectures and workshops, the current state of the treatment of motor, perceptual, pervasive, and language disorders in children. Our knowledge of these fields has certainly increased in recent years. DMC...

1Department of Medical Research, Chung Shan Medical University Hospital, Taichung 402, Taiwan 2Institute of Biochemistry and Biotechnology, Chung Shan Medical University, Taichung 402, Taiwan 3Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan 4Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077 5Tissue Culture ...

Natural products such as plant extracts and complex microbial secondary metabolites have recently attracted the attention of scientific world for their potential use as drugs for treating chronic diseases such as Type II diabetes. Non-Insulin-Dependent Diabetes Mellitus (NIDDM) or Type II diabetes has complicated basis and has various treatment options, each targeting different mechanism of act...

The thymus gland is a lymphatic organ involved in lymphoid cell development and maturation. However, its embryologic origins come from the endoderm as epithelial outgrowths of the lower portion of the third pharyngeal pouches. Cells of these epithelial outgrowths grow into the surrounding mesenchyma and subsequently constitute the medullary areas of the lobules of the thymus. In some areas, epi...

We present studies using natural bond orbitals (NBOs) as a starting point for a localized electron correlation treatment, as these kind of localized orbitals lead to CCSD results which show significant transferability and exponential decay patterns in the T̂2 amplitudes. The NBO CCSD approach combines the advantages of both the HF CCSD formulation (less amplitudes, orthogonal orbitals) and the A...

http://bmj.com/cgi/content/full/328/7430/30 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/328/7430/30/DC1 "Additional references" References http://bmj.com/cgi/content/full/328/7430/30#otherarticles 13 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/328/7430/30#BIBL This article cites 2...

We describe here the main natural compounds used in cancer therapy and prevention, the historical aspects of their application and pharmacognosy. Two major applications of these compounds are described: as cancer therapeutics and as chemopreventive compounds. Both natural compounds, extracted from plants or animals or produced by microbes (antibiotics), and synthetic compounds, derived from nat...

Atopic dermatitis is an inflammatory skin disease with early onset and with a lifetime prevalence of approximately 20%. The aetiology of atopic dermatitis is unknown, but the recent discovery of filaggrin mutations holds promise that the progression of atopic dermatitis to asthma in later childhood may be halted. Atopic dermatitis is not always easily manageable and every physician should be fa...