natural killer cells

Introduction: Immunological processes play an important role in recurrent spontaneous abortion(RSA). According to studies, T lymphocytes and natural killer cells(NK cells) are two effective cell groups in RSA. The aim of this study was to study the percentage and absolute number of natural killer(NK) cells in women with RSA of unknown etiology. Methods: A total of 24 women with history of recu...

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Fasting Enhances TRAIL-Mediated Liver Natural Killer Cell Activity via HSP70 Upregulation

2014

Vu T. A. Dang Kazuaki Tanabe Yuka Tanaka Noriaki Tokumoto Toshihiro Misumi Yoshihiro Saeki Nobuaki Fujikuni Hideki Ohdan

Acute starvation, which is frequently observed in clinical practice, sometimes augments the cytolytic activity of natural killer cells against neoplastic cells. In this study, we investigated the molecular mechanisms underlying the enhancement of natural killer cell function by fasting in mice. The total number of liver resident natural killer cells in a unit weight of liver tissue obtained fro...

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recombinant lpg3 stimulates ifn-γ and tnf-α secretion by human nk cells

Journal: :iranian journal of parasitology 0

sanaz rasolzadeh drug applied research center, tabriz university of medical sciences, tabriz, iran and dept. of immunology, faculty of medicine, tabriz university of medical sciences, tabriz, iran mostafa haji fatahaliha drug applied research center, tabriz university of medical sciences, tabriz, iran and dept. of immunology, faculty of medicine, tabriz university of medical sciences, tabriz, iran maryam hosseini drug applied research center, tabriz university of medical sciences, tabriz, iran and dept. of immunology, faculty of medicine, tabriz university of medical sciences, tabriz, iran reza jafari drug applied research center, tabriz university of medical sciences, tabriz, iran and dept. of immunology, faculty of medicine, tabriz university of medical sciences, tabriz, iran abolfazl miahipour dept. of medical parasitology and mycology, school of medicine, alborz university of medical sciences, karaj, iran ali akbar movassaghpour drug applied research center, tabriz university of medical sciences, tabriz, iran and dept. of immunology, faculty of medicine, tabriz university of medical sciences, tabriz, iran

background: natural killer (nk) cells play an important role in early stages of innate immune responses against viral and tumoral attacks. activation of nk cells by leishmaniasis results in secretion of cytokines such as interferon (ifn)-γ and tumor necrosis factor (tnf)-α, which enhances the phagocytosis and clearance of parasite. lipophosphoglycan 3 (lpg3), the leishmania homologous with grp...

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