Trans-acting small interfering RNAs (ta-siRNAs) and natural cis-antisense siRNAs (cis-nat-siRNAs) are recently discovered small RNAs (sRNAs) involved in post-transcriptional gene silencing. ta-siRNAs are transcribed from genomic loci and require processing by microRNAs (miRNAs). cis-nat-siRNAs are derived from antisense RNAs produced by the simultaneous transcription of overlapping antisense ge...

Natural antisense transcripts (NATs) are complementary to protein coding genes and potentially regulate their expression. Despite widespread occurrence of NATs in the genomes of higher eukaryotes, their biological role and mechanism of action is poorly understood. Zebrafish embryos offer a unique model system to study sense-antisense transcript interplay at whole organism level. Here, we invest...

Ustilago maydis infection of Zea mays leads to the production of thick-walled diploid teliospores that are the dispersal agent for this pathogen. Transcriptome analyses of this model biotrophic basidiomycete fungus identified natural antisense transcripts (NATs) complementary to 247 open reading frames. The U. maydis NAT cDNAs were fully sequenced and annotated. Strand-specific RT-PCR screens c...

TP53 mutation patterns are associated with prognosis of various cancers. This study was designed to investigate the association between TP53 mutation patterns and recurrence patterns in upper urinary tract urothelial carcinoma (UTUC) patients. A total of 165 consecutive UTUC patients who underwent nephroureterectomies were enrolled for measuring mutation patterns of TP53 gene from exome 2 to 11...

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The recently described complex nature of some dehydrin-coding sequences in Trifolium repens could explain the considerable variability among transcripts originating from a single gene.1 For some of the sequences the existence of natural antisense transcripts (NAT s), which could form sense-antisense (SAS) pairs, was predicted. The present study demonstrates that cis-natural antisense transcript...

ion of Γ, x : N `M : N nat× σ (γ × nat)× σ M ∀σ. Abstraction of Γ, x : N `M : Nion of Γ, x : N `M : N nat× σ (γ × nat)× σ M ∀σ. nat× σ′ (γ × nat)× σ′ γ × σ nat× (γ × σ′) Abstraction of Γ, x : N `M : Nion of Γ, x : N `M : N nat× σ (γ × nat)× σ M ∀σ. nat× τ γ × σ ∀σ.∃φ.∀τ . φ× σ (φ× nat)× τ nat× (φ× τ) λx:X.M Abstraction of Γ, x : N `M : Nion of Γ, x : N `M : N nat× σ (γ × nat)× σ M ∀σ. nat× τ γ ...

NATURE METHODS | ADVANCE ONLINE PUBLICATION | 1 is unlikely to misfold or aggregate in cells12. We hypothesized that some of the many BphP sequences in protein sequence databases might be monomeric in the BphP form, which is likely to occur if the protein lacks strong hydrophobic interactions at the putative dimer interface. In contrast, in IFP1.4’s parent, DrBphP13, the dimer interface include...

This document defines basic terminology for describing different types of Network Address Translation (NAT) behavior when handling Unicast UDP and also defines a set of requirements that would allow many applications, such as multimedia communications or online gaming, to work consistently. Developing NATs that meet this set of requirements will greatly increase the likelihood that these applic...

The Journal of Clinical Investigation | May 2003 | Volume 111 | Number 9 14. Abramsson, A., et al. 2002. Analysis of mural cell recruitment to tumor vessels. Circulation. 105:112–117. 15. Benjamin, L.E., Golijanin, D., Itin, A., Pode, D., and Keshet, E. 1999. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J. Clin. ...