OBJECTIVES Local recurrence of rectal cancer reduces quality of life and survival. A multi-factorial linear logistic model was used to analyse risk factors for local recurrence in rectal cancer in patients not receiving preoperative chemo-radiation. METHODS A case-control study of patients with rectal cancer having surgery with curative intent, between 1996 and 2008. Eighteen putative risk fa...

PURPOSE When faced with biochemical recurrence after definitive radiotherapy for prostate cancer, clinicians must determine whether the recurrence is local or systemic. Post radiotherapy prostate biopsies to detect persistent local disease are difficult to interpret histopathologically and are subject to sampling error. Our study examines outcomes for patients with a negative prostate biopsy pe...

results there was no statistical difference between the 2 groups with respect to the recurrence rate (p > 0.05). although the recurrence interval was longer for the metformin group, this increase was not statistical significant (p > 0.05). furthermore, tumor recurrence had no correlation with sex or the grade of the tumors. conclusions according to our findings, it seems that metformin has no c...

Local recurrence of rectal cancer is the result either of potentially removable tumor cells left in situ or cells already disseminated to areas where surgery cannot reach them. The first scenario infers inadequate surgery, the second implies unfavorable biology. Surgeons who operate for rectal cancer must know local recurrence rates in their patients, and be able to relate them to outcomes achi...

PURPOSE Little is known about local recurrence following proximal gastrectomy in patients with upper third gastric cancer. We performed this study to evaluate the long-term results of a proximal gastrectomy, and to analyze the risk factors of local recurrence affecting survival in these patients. MATERIALS AND METHODS We undertook a retrospective study of 63 patients who underwent potentially...

Although radiation therapy is effective in the management of patients with early stage nasopharyngeal cancer, a high rate of local-regional failure and distant dissemination is expected in patients with advanced disease. This has prompted studies on the addition of chemotherapy to radiation therapy. Chemotherapy has been used as a neoadjuvant and, less frequently, concomi-tantly with radiation ...

Lymphoepithelioma-like carcinoma of the skin (LELCS) is a rare cutaneous neoplasm microscopically similar to undifferentiated nasopharyngeal carcinoma. It is typically nonaggressive and is treated with wide local excision. However, we present a case of a patient with a regional recurrence and more aggressive LELCS with perineural invasion and positive margins for which he was treated with wide ...

Abstract Objectives In nasopharyngeal carcinoma (NPC), the main factors for treatment failure are local recurrence and metastasis. Vasculogenic mimicry (VM), formation by invasive cancer cells mimicking vasculogenic network, is strongly correlated with tumor therapy resistance distant CSF-1R was substantially expressed in NPC patients a poor prognosis, according to an earlier study of ours. How...