OBJECTIVE To study differences between aspirin-tolerant patients and aspirin-intolerant patients concerning vascular endothelial growth factor (VEGF) expression. Recent publications strongly suggest the involvement of VEGF and its receptors in the pathophysiologic process of nasal polyps. DESIGN We subjected 43 polyp specimens to semiquantitative immunohistochemical analysis. We quantified VE...

OBJECTIVE To clarify the relationship between prostaglandin D2 production and eosinophil accumulation. DESIGN Screening and diagnostic tests. SUBJECTS Nineteen patients with chronic rhinosinusitis. INTERVENTIONS Nasal polyps were obtained from 19 patients at endoscopic sinus surgery. Eosinophils in nasal polyps were counted after hematoxylin-eosin staining and immunostaining with antibodi...

OBJECTIVE: The aims of this study were to investigate the prevalence and distribution sinonasal diseases in patients that underwent paranasal sinus computed tomography (CT) due chronic rhinosinusitis (CRS) with or without nasal polyps, explore association between CRS variations effect environmental factors.MATERIAL AND METHODS: CT images files 1000 referred a tertiary health center Ankara retro...

Isolated sphenoid pathology is uncommon. Nasal polyps that originate from the anterior wall of the sphenoid sinus and reach the nasopharynx are called sphenochoanal polyps. The atypical location of sphenochoanal polyps leads to misdiagnosis, and surgery risks injuring the surrounding structures, such as the optic nerve, carotid artery, and brain. For the differential diagnosis of sphenochoanal ...

Nasal polyp is a chronic inflammatory disease affecting about 1–4% of the general population. polyps are fleshy benign growth that develop in mucosal lining nasal passage and paranasal sinuses. Polyps vary size having shining pink colour shaped like grapes. The exact etiology remains unclear but it known to have associations with allergy, asthma, infection. common features obstruction, anosmia,...

The aim of the present study was to investigate the expression, distribution and function of dendritic cells (DCs) and to study their role in nasal polyps. The study involved 55 participants, 45 of whom had nasal polyps and were the study group and 10 who had normal inferior turbinates and were the control group. Immunohistochemical staining was used to visualize the expression and distribution...

BACKGROUND Asthmatic nasal polyps primarily exhibit eosinophilic infiltration. However, the identities of the immune cells that infiltrate non-asthmatic nasal polyps remain unclear. Thus, we thought to investigate the distribution of innate immune cells and its clinical relevance in non-asthmatic chronic rhinosinusitis (CRS) in Korea. METHODS Tissues from uncinate process (UP) were obtained f...

Endoscopy is needed for reliable evaluation of the treatment of nasal polyposis. In this study, we compared the reproducibility of various score systems for staging nasal polyposis and the inter-individual variations between investigators. The mass of the polyps was assessed by five methods, three new techniques (numbers 1, 2 and 3) and two established ones (numbers 4 and 5). These were: 1, lat...

Nasal polyps,the prolapsed linings of nasal mucosa are one the commonly encountered conditions in theoutpatient department otolaryngology, The aim this study is to etiology polyps andalso compare between different methods used for diagnosis polyps.This was submitted prospectively on 100 patients diagnosed with (diagnosed eitherclinically or radiologically) evidence obstruction,rhinorrhae and he...

A 77-year-old man presented with long periods of left-sided nasal obstruction and intermittent epistaxis. Nasal fibroscopy revealed an unusual, white, cauliflower-like, well-circumscribed, firm polypoidal mass arising from the vertebral portion of the left inferior turbinate (Figure 1). The surface of the multilocular polyps was lustrous. Computed tomography showed soft-tissue opacity with no e...