the aim of me present work was to investigate rhe potential utility of nanoparticles made of chitosan (cs) and also cs chemically modified with polyethylene glycol (cs-peg) as new vehicles for improving na^al vaccine delivery. for mis purpose, diphtheria toxoid (dt) was chosen as a model antigen. dt was entrapped within nanoparticles made of cs of different molecular weight, and also made of cs...

introduction: a reduction or cessation of the ability to breathe through the nose can affect a person's overall health. nasal passage blockage can also result in snoring. difficulty in breathing through the nose after rhinoplasty is a serious problem and patient dissatisfaction can be significant even when cosmetic results are excellent. long-term impacts on the quality of life and contrib...

a 74 yr old woman from gonabad, southern part of khorasan razavi province of iran was admitted to a hospital of gonabad, because of respiratory distress, exertional dyspnea and fever. close contact with domes­tic animals, history of chronic obstructive pulmonary disease (copd), and completely resolved pulmonary tuberculosis (tb) in remote past, were nota­ble parts of her past medical history. d...

history and objectives: insertion of intragastric tube through nose in infants for evaluation of congenital abnormalities of nose, esophagus and stomach in early hours after birth can lead to some complications (bradycardia, apnea and/or cyanosis) as a result of the stimulation of receptors of pharynx. this study was carried out to determine the complications in javaheri hospital affiliated to ...

background nasal colonization of healthy children with staphylococcus aureus is an important risk factor for different infections. detection of colonized individuals with methicillin resistant s. aureus (mrsa) and its eradication is the proper prevention strategy for infection spread in the community and health-care centers. objectives the aim of this study was to determine the prevalence, asso...

Introduction: The Study Aimed To Compare The Results of Cryosurgery With Trichloroacetic Acid Chemical (TCA) Cautery For The Treatment of Hypertrophied Nasal Turbinates.   Materials and Methods: This was a prospective study of 70 patients with nasal obstruction due to hypertrophied nasal turbinates who were randomly divided in 2 groups of 35 each. In group 1, patients underwent inferior nas...

the objective of this investigation was the development of chitosan/xanthan polyelectrolyte complex based mucoadhesive nasal insert of promethazine hydrochloride a drug used in the treatment of motion sickness. a 32 factorial design was applied for preparing chitosan/xanthan polyelectrolyte complex and to study the effect of independent variables i.e. concentration of xanthan [x1] and concentra...

although several treatments have been suggested for nasal polyposis, from medical to surgical, there is no standard guideline for the management of this disease. during recent years increasing attention has been directed toward the effects of macrolide antibiotics on chronic sinusitis and nasal polyposis. in this study,  the efficacy of clarithromycin on severe nasal polyposis were examined. in...