The genus Astronium (Anacardiaceae) includes species, such as Astronium fraxinifolium, Astronium graveolens, and Astronium urundeuva, which possess anti-inflammatory, anti-ulcerogenic, healing, and antimicrobial properties. Nanostructured lipid systems are able to potentiate the action of plant extracts, reducing the required dose and side effects and improving antimicrobial activity. This work...

Thanks to their outstanding advantages, nanostructured lipid carriers (NLCs) have recognized in various fields these days. One way to discover extra useful products against typical bacteria (e.g., Staphylococcus epidermidis) is NLCs loaded with essential oils. This paper aims to provide NLCs to encapsulate MA oil and characterize and survey the obtained MA...

Objective: Vitamin E acetate has antioxidant activity that can prevent premature aging of the skin, but it is highly lipophilic (log p±12.2) and potentially degraded. To overcome permeability stability problems, vitamin needs to be developed in Nanostructured Lipid Carrier (NLC), a nano-delivery system based on solid lipid liquid stabilized by surfactants as colloidal system.
 Methods: The...

BACKGROUND Thymoquinone (TQ), the predominant active lipophilic component in Nigella sativa seed oil, has a variety of pharmacological properties such as anticancer activities. However, translation of TQ to clinical phase is still not possible due to its hydrophobic properties. This problem can be solved by encapsulating it in nanoformulations to enhance its pharmacological properties. In our p...

solid lipid carriers – NLC. Particulate lipid matrices in the form of lipid pellets are known from the textbooks since many years, products are on the market (e. g. Mucosolvan retard, Boehringer-Ingelheim). After these lipid pellets as the first generation, P. Speiser developed so-called “lipid nanopellets for oral administration” in the middle of the eighties [1]. This system was not further d...

A Nanostructured lipid carrier (NLC) is an emulsion system that can encapsulate and improve stability of lipid-based bioactive compounds. This study aimed to develop optimal RPO-NLC formula with a combination solid liquid lipids, lipids surfactants, the use high-pressure homogenizer (HPH). was made using HPH 400 bar 600 pressure. Completely randomized design (CRD) three factors used determine i...