نتایج جستجو برای: nanosilica and drug delivery
تعداد نتایج: 16916900 فیلتر نتایج به سال:
Nowadays, design and synthesis of efficient drug delivery systems are of vital importance in order to optimize the efficacy of therapeutics and reducing side effects. So far, many drug delivery systems have been designed, among them, natural polymer-based systems have attracted the most attention. Silk fibroin (SF) as a natural polymer have several unique properties including excellent biocompa...
The objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (DDS) for Metoprolol tartarate (MT) as tablet and capsule. Pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal del...
To answer challenge of targeted and controlled drug release in oral delivery various materials were studied by different methods. In the present paper, controlled metal based drug (Pd(II) complex) release manner of β‑Lactoglobulin (β-LG) nanoparticles was investigated using mathematical drug release model in order to design and production of a new oral drug delivery system for gastrointestinal ...
Recently, Carbon Nano (CN) structures are widely used in medical applications, especially the detection and treatment of cancer disease. Among various types of CNs, Carbone Nano Tubes (CNTs) attracted many researchers' attention to consider them toward clinical application. Regarding the intrinsic structure of CNTs, they can be used widely in drug delivery applications. Functionalized CNTs and ...
PEGylated polypropyleneimine (PPI) dendritic scaffold was used for the delivery of an anti-leukemic drug, Imatinib. The current study evolves and emerges the use PEGylated PPI dendritic scaffold for the delivery of this drug. In this Imatinib was synthesized and loaded with PEGylated PPI dendritic scaffold. Parameters such as FT-IR, NMR, SEM, drug release, DSC and hemolytictoxicity are required...
PEGylated polypropyleneimine (PPI) dendritic scaffold was used for the delivery of an anti-leukemic drug, Imatinib. The current study evolves and emerges the use PEGylated PPI dendritic scaffold for the delivery of this drug. In this Imatinib was synthesized and loaded with PEGylated PPI dendritic scaffold. Parameters such as FT-IR, NMR, SEM, drug release, DSC and hemolytictoxicity are required...
a great challenge in using natural polysaccharide as drug delivery system is their fast drug release. the purpose of the present study was to prepare and evaluate chitosan oligosaccharide (cho)-de-estrifiedtragacanth (det) core-shell nanoparticles for controled release of water soluble drugs. cho-det nanoparticles were prepared by microemulsion method and characterized by ft-ir spectroscopy. si...
objective(s): in a new approach, following the development in metal oxide chemistry, the ibuprofen as low water soluble nonsteroidal anti-inflammatory drug diffused into synthetic sol-gel derived nano porous g-alumina by an impregnation method in order to increase the solubility and control the drug release in physiological environment. methods: sol-gel method was utilized for the fabrication o...
Erosion is one of the main factors of destruction of hydraulic structures. Therefore, soil improvement is necessary to improve soil quality and reduce soil erosion. Due to the adverse effects of substances such as lime and ash and also the increasing usage of nanotechnology in various branches of engineering sciences, using nanoparticles as new additives is an efficient way. In this study, to i...
Collaboration in drug delivery is a project by which a pharmecutical product is delivered through the cooperation of two or more legal persons. In this cooperation, a party contributes to the project with know-how and formula of a medicine and the other party provides site, necessary fund and equepments. Success in such a project requires a legal agreement entitled collaboration contracts in dr...
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