Background: Onychomycosis is a very common and widespread disorder, however the incidence of onychomycosis in psoriatic patients is not accurately assessed. Objective: The present study was undertaken to evaluate the frequency of fungal infections of the nails changed in the course of psoriasis and to provide an answer whether psoriatic nails are specially predisposed to fungal infections. Mate...

ABSTRACT Introduction: Nail psoriasis treatment is challenging due to difficult drug delivery and systemic therapy toxicities. Self-dissolvable microneedle patches embedded with corticosteroids offers a potentially rapid, minimally invasive platform good efficacy minimal adverse side effects. Methods: We conducted 4-month prospective randomised controlled trial. Subjects psoriatic nails were re...

OBJECTIVE To study whether obesity increases the risk of psoriatic arthritis (PsA), given that obesity is a risk factor for psoriasis and is associated with more severe disease. DESIGN Case series. We used Cox regression analysis to study the relationship between obesity and PsA while controlling for age at psoriasis onset, current body mass index (BMI), sex, family history of psoriasis, wors...

OBJECTIVE To describe the clinical patterns of arthritis in psoriasis. STUDY DESIGN Cross-sectional, observational study. PLACE AND DURATION OF STUDY Combined Military Hospital, Kharian Cantonment, Pakistan, from January to December 2007. METHODOLOGY One hundred consecutive patients with psoriasis reporting to dermatology outpatient department were included. Pregnant ladies (due to X-ray ...

Twenty Nail Dystrophy (TND) is a rare acquired idiopathic nail dystrophy characterized by excess longitudinal ridging, distal notching, splitting, loss of nail luster and thinning of nail plates that may affect 1 to 20 nails. It occurs as a common manifestation of various dermatoses affecting the nail unit like lichen planus, psoriasis, atopic dermatitis, onychomycosis, vitiligo and alopecia ar...

OBJECTIVE To estimate the incidence of psoriatic arthritis (PsA) in patients with psoriasis, and to identify risk factors for its development. METHODS The study was designed as a prospective cohort study involving psoriasis patients who did not have a diagnosis of arthritis at the time of study enrollment. Information was collected about lifestyle habits, comorbidities, psoriasis activity, an...

OBJECTIVE To assess the extent to which UV-A and UV-B radiation can penetrate the human fingernail plate. DESIGN The Dermalite UV light machine (National Biological, Beachwood, Ohio) was used as the source of UV radiation. The amount of UV-A and UV-B penetrating the nail plate was measured using a radiometer and compared with a control. SETTING Academic phototherapy clinic. PATIENTS Ten c...