نتایج جستجو برای: n18

تعداد نتایج: 145  

Journal: :Journal of Crohn's and Colitis 2023

Abstract Background Native language-speaking patients with IBD may be underserved by an Anglo-centric delivery of healthcare in multicultural communities. We explored experiences Bangladeshi living the UK whose preferred languages were Bengali or Sylheti. Methods aged 18 years+, confirmed diagnosis Crohn’s disease, ulcerative colitis, who fully mostly spoke Sylheti, recruited from infusion clin...

Journal: :The Journal of biological chemistry 1991
J Parkkinen H Rauvala

The heparin-binding p30 protein amphoterin is proposed to mediate adhesive interactions of the advancing plasma membrane in migrating and differentiating cells. Since the NH2-terminal part of amphoterin is exceptionally rich in lysine residues, we have studied its interactions with plasminogen and tissue plasminogen activator (t-PA). On immunostaining of N18 neuroblastoma cells, amphoterin and ...

Journal: :Neurochemistry international 2012
Duo Jin Shin-Ichi Muramatsu Nobuaki Shimizu Shigeru Yokoyama Hirokazu Hirai Kiyofumi Yamada Hong-Xiang Liu Chiharu Higashida Minako Hashii Akihiko Higashida Masahide Asano Shoji Ohkuma Haruhiro Higashida

A 16-kDa proteolipid, mediatophore, in Torpedo electric organs mediates Ca(2+)-dependent acetylcholine release. Mediatophore is identical to the pore-forming stalk c-subunit of the V0 sector of vacuolar proton ATPase (ATP6V0C). The function of ATP6V0C in the mammalian central nervous system is not clear. Here, we report transfection of adeno-associated viral vectors harboring rat ATP6V0C into t...

2015
Varadharajan Thiyagarajan May-Jywan Tsai Ching-Feng Weng Habib Boukerche

Focal adhesion kinase (FAK) is a non-receptor protein tyrosine that is overexpressed in many types of tumors and plays a pivotal role in multiple cell signaling pathways involved in cell survival, migration, and proliferation. This study attempts to determine the effect of synthesized antroquinonol on the modulation of FAK signaling pathways and explore their underlying mechanisms. Antroquinono...

Journal: :The Journal of Cell Biology 1974
Karl W. Lanks Jan M. Dorwin Bruno Papirmeister

When neuroblastoma cells (N18) in vitro are maintained in the absence of serum, the specific activity of AChE begins to rise rapidly after an initial lag period of about 2-3 days, reaching a maximum level (10-20-fold increase) by 7 days after induction. In order to clarify the mechanism of induction, it was necessary to measure the rate of AChE synthesis and its sensitivity to metabolic inhibit...

Journal: :The Journal of pharmacology and experimental therapeutics 1998
C C Felder K E Joyce E M Briley M Glass K P Mackie K J Fahey G J Cullinan D C Hunden D W Johnson M O Chaney G A Koppel M Brownstein

LY320135 is a selective antagonist for the brain CB1 receptor, having greater than 70-fold higher affinity for the CB1 than the peripheral CB2 receptor. The Ki values for LY320135 at the CB1 and CB2 receptors, transfected and stably expressed in cell lines, were 224 nM and > 10 microM, respectively. Similar Ki values were measured in binding studies performed on cerebellum and spleen membrane p...

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