Simple synthetic routes to regioselectively deuterated tris[2-(dimethylamino)ethyl]amine (Me6TREN) variants are described. Imine formation with formaldehyde-d2 from tris(2-aminoethyl)amine (TREN) and subsequent reductions NaBD4 afforded N[CH2CH2N(CD3)2]3 or d18-Me6TREN in 79 % yield. A trisubstitution protocol 2-bromo-N,N-dimethylacetamide ammonium carbonate reduction of the N(CH2CONMe2)3 inter...

The Front Cover illustrates the photocatalytic reduction of CO2 to CO by an aniline-substituted Re-bipyridine-type photocatalyst in presence a strong electron donor (1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzo[d]-imidazole=BIH) N,N-dimethylacetamide. This catalyst absorbs visible light intensely compared related catalysts, and aniline moiety has beneficial effect on activity. More information ca...

An excess of elemental iodine in N,N-dimethylacetamide enables effective 3/iodanylium-de-hydronation of terminal alkenes with 3-iodopropene derivatives and hydrogen iodide formation within minutes at room temperature. The optimal molar ratio of iodine to substrate was decreased to 1 : 1 when hydrogen iodide formed was oxidized on a platinum anode. The electrolytic oxidation recovers iodine as a...

Two unprecedented 3D porous anionic metal-organic frameworks, [Me2NH2]2[Cd2(bpdc)3].4dma 1 and [Me2NH2]2[Cd2(NH2bdc)3].4dma 2 (dma = N,N'-dimethylacetamide, bpdc = 4,4'-biphenyldicarboxylate, NH(2)bdc = 2-amino-1,4-benzenedicarboxylate) have been solvothermally synthesized with a dimethylammonium cations template. Both 1 and 2 are constructed from low-symmetry SBUs. 1 has a chiral framework wit...

The surface tension at the liquid–air interface of eight binary mixtures formed by N,N-dimethylacetamide and n-alkanols (from methanol to 1-pentanol) or 2-alkanols 2-propanol 2-pentanol) was studied three different temperatures (283.15, 298.15, 313.15 K) a pressure 0.1 MPa. Surface deviations were also calculated. Moreover, excess molar enthalpies for all these measured T = 298.15 K Both deviat...

The highly efficient and selective production of 5-hydroxymethylfurfural (HMF) from sucrose has been achieved in the presence of metal chlorides and ammonium halides under mild conditions. Notably, an 87% yield of HMF from sucrose was obtained with a catalyst system composed of CrCl(3) and NH(4)Br at 100°C for 1.0 h in N,N-dimethylacetamide (DMAc) solvent. The effect of the reaction temperature...

Electrospinning is a simple method for producing ultrafine fibers, and has attracted much recent interest. The classical approach was either polymer solutions or polymer melts. Bubbfil spinning (e.g. bubble-electrospinning) is a facile method to fabricate nanofibers with high surface area to volume ratio and high porosity. Polyether sulfone (PES) dissolved in N,N-Dimethylacetamide (DMAC) was us...

The synthetic route for a uterine relaxant, bis(2-[[(2S)-2-([(2R)-2-hydroxy-2-[4-hydroxy-3-(2-hydroxyethyl)-phenyl]ethyl]amino)-1,2,3,4-tetrahydronaphthalen-7-yl]oxy]-N,N-dimethylacetamide) sulfate (KUR-1246), was established by the coupling of optically active components, the bromohydrin 14 and the amine 24. We now describe the practical synthesis of these two optically active components. Brom...