Herein, a straightforward synthesis of novel class polymers, that is, poly(N-(4-vinylphenyl)sulfonamide)s, and their monomers is reported. A set with varying electron densities, fine-tuned by different substituents on the aromatic sulfonamide moiety, polymerized free radical polymerization featuring low molar masses (2300 ≤ Mn 3200 g mol−1) dispersities (1.15 Đ 1.47). Further, post-polymerizati...

BACKGROUND The red fluorescent dye Sulforhodamine 101 (SR101) has been used in neuroscience research as a useful tool for staining of astrocytes, since it has been reported as a marker of astroglia in the neocortex of rodents in vivo. The aim of this work is to label SR101 with positron emission radionuclides, in order to provide a radiotracer to study its biological behavior. This is the first...

N-substituted benzenesulfonamides, incorporating the N-amino-, N-hydroxy- and N-methoxy-moieties at the sulfonamide zinc binding group, have been investigated as CAIs by means of inhibition and structural studies, unraveling interesting aspects related to their inhibition mechanism.

The design of novel supramolecular synthons for functional groups relevant to drugs is an essential prerequisite for applying crystal engineering in the development of novel pharmaceutical cocrystals. It has been convincingly shown over the past decade that molecular level control and modulation can influence the physicochemical properties of drug cocrystals. Whereas considerable advances have ...

1. The chief sulphur-containing metabolite of styrene and sytrene oxide in the rabbit and rat is chromatographically identical with N-acetyl-S-(beta-hydroxyphenethyl)-l-cysteine and this compound is also formed, together with N-acetyl-S-phenethyl-l-cysteine, as a metabolite of phenethyl bromide. 2. The amounts of the phenethylmercapturic acid and its hydroxy derivative excreted in the urine of ...

The title compound, C12H18N4O6S (systematic name: 4-di-propyl-amino-3,5-di-nitro-benzene-sulfonamide), is a sulfonamide with herbicidal properties marketed as oryzalin. The dihedral angles between the benzene ring and the mean planes of the nitro groups are 26.15 (11) and 54.80 (9)°. The propyl arms of the di-propyl-amino substituent lie on opposite sides of this ring plane. In the crystal, N-H...