Among ploidy groups in childhood acute lymphoblastic leukemia (ALL), hyperdiploidy 47 to 50 is perhaps the least well known. From December 1979 to December 1990, we successfully studied banded karyotypes in 598 cases of newly diagnosed ALL, of which 86 (14.4%) had modal chromosome numbers of 47 to 50. In this group, the most frequently acquired numerical abnormalities were +21 (n = 34), +X (18)...

With the development of carbonate clumped isotope (?47) geothermometer, many ?47–temperature calibrations based on biogenic and abiogenic carbonates have been generated in recent years. However, there is still not a robust empirical calibration relationship derived from lacustrine authigenic that can be used to calculate lake water temperatures ?47 values. In this study, we present new dataset ...

OBJECTIVE To study the prevalence of psychiatric disorders in children affected by the Asian tsunami in Ranong province, Southern Thailand 10 months after the disaster. SUBJECTS AND METHODS The subjects were 47 boys and 47 girls, age 1-18 years, who were affected by the tsunami. They were participants in the Psychosocial Care and Protection System for Tsunami-Affected Children in Ranong Provi...

Carrithers, Stephen L., Sammy L. Eber, Leonard R. Forte, and Richard N. Greenberg. Increased urinary excretion of uroguanylin in patients with congestive heart failure. Am. J. Physiol. Heart Circ. Physiol. 278: H538–H547, 2000.—Uroguanylin is a small-molecular-weight peptide that activates membrane-bound receptor-guanylate cyclases in the intestine, kidney, and other epithelia. Uroguanylin has ...

Husted, Russell F., Rita D. Sigmund, and John B. Stokes. Mechanisms of inactivation of the action of aldosterone on collecting duct by TGF-b. Am. J. Physiol. Renal Physiol. 278: F425–F433, 2000.—The purpose of these experiments was to investigate the mechanisms whereby transforming growth factor-b (TGF-b) antagonizes the action of adrenocorticoid hormones on Na1 transport by the rat inner medul...

Dinenno, Frank A., Pamela P. Jones, Douglas R. Seals, and Hirofumi Tanaka. Age-associated arterial wall thickening is related to elevations in sympathetic activity in healthy humans. Am J Physiol Heart Circ Physiol 278: H1205–H1210, 2000.—Arterial wall hypertrophy occurs with age in humans and is a strong predictor of cardiovascular disease risk. The responsible mechanism is unknown, but data f...