The origin of the eukaryotic cell nucleus and the selective forces that drove its evolution remain unknown and are a matter of controversy. Autogenous models state that both the nucleus and endoplasmic reticulum (ER) derived from the invagination of the plasma membrane, but most of them do not advance clear selective forces for this process. Alternative models proposing an endosymbiotic origin ...

Kingsbury, David T. (University of Washington, Seattle), and Erling J. Ordal. Bacteriophage infecting the myxobacterium Chondrococcus columnaris. J. Bacteriol. 91:1327-1332. 1966.-During a series of screening experiments, seven bacteriophages which infect the pathogenic myxobacterium Chondrococcus columnaris were isolated. Of these, one was chosen for detailed study. This phage has a wide host ...

BACKGROUND Disorazoles are polyene macrodiolides isolated from a myxobacterium fermentation broth. Disorazole C1 was newly synthesized and found to depolymerize microtubules and cause mitotic arrest. Here we examined the cellular responses to disorazole C1 in both non-cancer and cancer cells and compared our results to vinblastine and taxol. RESULTS In non-cancer cells, disorazole C1 induced ...

Studies on Toxin Production of Clostridium botulinum Type E. III. Characterization of Toxin Precursor. GENJI SAKAGUCHI AND SUMIKO SAKAGUCHI.......... 1-9 Kanamycin Resistant Staphylococcus Mutant Requiring Heme for Growth. DIRAN YEGIAN, GLORIA GALLO, AND M. WILSON TOLL.............................. 10-12 Serological Types of Escherichia coli in Association with Infantile Gastroenteritis. G. S. ...