BACKGROUND/OBJECTIVES In this study, potential anti-inflammatory effect of enzymatic hydrolysates from Styela clava flesh tissue was assessed via nitric oxide (NO) production in lipopolysaccahride (LPS) induced RAW 264.7 macrophages and in vivo zebrafish model. MATERIALS/METHODS We investigated the ability of enzymatic hydrolysates from Styela clava flesh tissue to inhibit LPS-induced express...

We present a methodology to quantitatively determine the fraction of sodium dodecyl sulfate (SDS) that partitions to the oil/water interface in oil-in-water macroemulsions and calculate the total interfacial area (TIA) through the novel use of filtration through nanoporous membranes. Ultrafiltration was carried out in centrifuge tubes having nanoporous filters with a 30,000 molecular weight cut...

Infection by the human hookworm Necator americanus is a leading cause of anemia and disability in the developing countries of Africa, Asia, and the Americas. In order to prevent childhood hookworm disease in resource poor settings, a recombinant vaccine is under development by the Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, a Product Development Partner...

Reverse Osmosis systems are wildly used for sea water desalination and water reclamation but they meet problems regarding bio-fouling. Bio-fouling increases their work pressure and operational costs and decreases their removal efficiencies. Phosphorus limitation is one strategy to control bio-fouling. This report focuses on phosphorus removal by ceramic tight ultra-filtration (CTUF) membranes (...

The utilisation of plant-derived nanoscale cellulosic materials (cellulose nanofibrils, CNF) in tailoring water purification membranes is constantly gaining interest the context green-functionalised membrane solutions. However, most existing approaches based on renewable and biobased suffer from lack efficient scalable processing strategies. Here, we introduce a roll-to-roll modification approa...

Whey proteins are a rich source of angiotensin converting enzyme I (ACE) inhibitory peptides. The ACE inhibition is one of the key mechanisms by which reduction in blood pressure is exerted in the body so some of these peptides have also shown a blood pressure reduction effect ie, antihypertensive activity. They can therefore be part of a dietary intervention to treat this health condition. The...

BACKGROUND Lentiviral vectors (LVs) can efficiently transduce a broad spectrum of cells and tissues, including dividing and non-dividing cells. So far the most widely used method for concentration of lentiviral particles is ultracentrifugation (UC).An important feature of vectors derived from lentiviruses and prototypic gamma-retroviruses is that the host range can be altered by pseudotypisatio...

Secreted proteins by cardiomyocytes, including paracrine factors and extracellular matrix proteins provide a means of communication in the heart between myocytes and non-myocytes. Heart disease encompasses a broad spectrum of pathological conditions and abnormal changes to the proteome can reflect these various disease states. In this project we set out to identify differentially secreted prote...