Knowledge of the appearances of normal bone marrow, metastases involving marrow, and therapy-related marrow changes shown by MR imaging is necessary in order to avoid misdiagnosis. This article reviews MR imaging techniques and the findings that allow distinction of normal yellow (fatty) marrow and red marrow from tumor in marrow, as well as the identification of marrow changes resulting from r...

Determining the presence or absence of neurovascular involvement by a malignant musculoskeletal neoplasm is an important aspect of local tumor staging. This article discusses issues concerning such assessments made by diagnostic imaging techniques, including factors inherent to the patient and those related to imaging technology. The distinction between tumor contact and tumor encasement is emp...

BACKGROUND In recent years, scientific research has increasingly focused on malignancies during pregnancy. However, the development of musculoskeletal tumors during pregnancy has only been the subject of a few studies so far. The primary aim of this study was to identify the incidence of sarcomas during pregnancy at our musculoskeletal tumor center (MSTC). Secondarily we intended to analyze the...

UNLABELLED Resection of musculoskeletal tumors may result in large soft tissue defects that cannot be closed primarily and require prolonged dressing changes and complex surgical interventions for wound coverage. We retrospectively reviewed 23 patients with such defects treated with a vacuum-assisted wound closure system and compared the outcome of these patients with a control group. The study...

In the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis usually depends on histologic analysis by an experienced pathologist. Biopsy is a very important ...

BACKGROUND D-dimer (DD) levels have been reported as a sensitive but non-specific indicator for deep vein thrombosis (DVT) and pulmonary embolism (PE). Few reports have examined perioperative DD levels in musculoskeletal tumor. MATERIALS/METHODS Subjects comprised 77 patients who had undergone oncological resection of musculoskeletal tumor. DD levels were assessed preoperatively and on postop...

OBJECTIVE Sarcomas are rare mesenchymal malignancies. Accurate preoperative diagnosis is a prerequisite in considering investigational or institutional management algorithms that include neoadjuvant treatment. We reviewed our experience using core needle biopsy for chest wall sarcomas. METHODS A retrospective review of our sarcoma databases revealed that 40 core needle biopsies and 35 tumor r...