When one considers the many types of chemical compound used in modern therapeutics, it is not surprising that some of these modify the action of muscle relaxants. In general such substances may interfere with neuromuscular transmission, or may influence relaxants by actions at other sites. Some such side effects are well known. Others, based on animal experiments on many different species and u...

Objective: Primary care, which is often the first level of contact for patients with various communicable diseases (CDs) and noncommunicable (NCDs), might exhibit patterns injectable drug utilization different from hospitals. We aimed to examine injection prescribing adults CD or NCD in primary care. Methods: In this retrospective study, single-diagnosis drug-containing prescription data Family...

Myasthenia Gravis is an autoimmune neuromuscular disorder of skeletal muscles due to the presence of acetylcholine receptor antibodies. Myasthenic patients are resistant to depolarizing relaxants such as succinylcholine but are very sensitive to non-depolarizing muscle relaxants1. That’s why, narcotic-based technique for induction and maintenance of anesthesia without muscle relaxants has been ...

T H E increasing understanding of the mechanism of action of the muscle relaxants has led to a high degree of safety in their use. Nevertheless, the occasional patient is still encountered in whom the response to the drug is greater than anticipated. There are already a number of reports in the literature outlining the almost unlimited number of causes for this prolonged response (Paton, 1958; ...

BACKGROUND Recent studies suggest advantages of muscle relaxants for facemask ventilation. However, direct effects of muscle relaxants on mask ventilation remain unclear because these studies did not control mechanical factors influencing ventilation. We tested a hypothesis that muscle relaxants, either rocuronium or succinylcholine, improve mask ventilation. METHODS In anesthetized adult per...