In the original publication, the article title was incorrectly published as ‘Successful Management of Zoon’s Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris’. The correct title should read as ‘Successful Management of Zoon’s Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Revie...

The in vitro activities of mupirocin, quinupristin/dalfopristin, linezolid, eperezolid, sitafloxacin, clinafloxacin, moxifloxacin, amoxycillin, metronidazole and clarithromycin were tested at pH 7.4 against 57 strains of Helicobacter pylori. The most active agents (mupirocin, sitafloxacin and clinafloxacin) were also tested for activity at pH 5.4 against the same strains. Mupirocin was very act...

Mupirocin is used for eradicating methicillin-resistant S. aureus (MRSA) nasal colonisation. A plasmid-borne gene, mupA, is associated with high-level mupirocin resistance. After the prevalence of mupA, encoding high-level mupirocin resistance, among all MRSA from a tertiary care centre in the German state of Saxony was approximately 1% for over 15 years (2000-2015), a sharp increase to nearly ...

OBJECTIVES Recently, there have been increasing concerns about the emergence of mupirocin resistance and increased infections due to lowered inhibition of Staphylococcus aureus. We conducted this systemic analysis to find out whether the application of mupirocin was effective for the prevention of exit-site infection (ESI) and peritonitis in patients undergoing peritoneal dialysis (PD). METHO...

Methicillin-resistant Staphylococcus aureus (MRSA) is difficult to treat, causing considerable morbidity and mortality. Nasal carriage of MRSA can occur both in healthcare workers patients. Mupirocin used as a topical agent for the eradication such isolates. The present study aims prevalence mupirocin resistance among MSSA (Methicillin-sensitive aureus) A total 148 isolates were tested. Antibio...

Objective: To evaluate the impact of the use of topical Mupirocin on the insertion of central venous catheter for hemodialysis. Methods: This was a systematic review with meta-analysis. Results: After a careful and extensive search, we included three clinical trials that compared the use of Mupirocin versus other intervention in central venous catheter for hemodialysis. Conclusion: The study fo...

A plasmid known to be associated with mupirocin resistance of Staphylococcus aureus has been isolated and a restriction enzyme map constructed. An EcoRI fragment of 4.05 kb from this plasmid has been cloned into an Escherichia coli-Staphylococcus aureus shuttle vector and shown to carry the gene for resistance to mupirocin. The DNA sequence of a small section of the gene has been determined and...

Prophylactic mupirocin for peritoneal catheter exit sites reduces exit site infection (ESI) risk but engenders antibiotic resistance. We present early interim safety analysis of an open-label randomized study comparing polyhexamethylene biguanide (PHMB) and mupirocin. A total of 106 patients randomized to 53 in each group were followed up for a mean of 12.68 months per patient. On safety analys...

We identified 25 high-level mupirocin-resistant (MuH) and 21 low-level mupirocin-resistant (MuL) Staphylococcus aureus isolates from eight long-term-care facilities (LTCFs). The pulsed-field gel electrophoresis patterns of 19 MuH and 19 MuL isolates from two facilities were identical for 18 and 15 isolates, respectively. The most predominant mupA restriction fragment length polymorphism type wa...