We present the case of a 39-year-old woman with an eggshaped tumor on the lateral aspect of her right ankle below the lateral malleolus, measuring 3.2 cm. The lesion was detected by the patient 3 years before she came to the clinic; however, it produced pain when walking only a year before her visit. The tumor was painful on palpation and had a hard consistency (Fig. 1A). An ultrasound with Esa...

We demonstrated that the expression of 14-3-3 gamma was lower in uterine leiomyomas compared to the adjacent normal myometrium. Here, we show that 14-3-3 gamma promoter is methylated more in leiomyomas than myometrium. The level of 14-3-3 gamma protein in leiomyomas did not change in respect to age, size, location, or the type of leiomyoma. ER-alpha, ER-beta, and PR proteins were also higher in...

more than 90% of patients infected with cutaneous leishmaniasis live in afghanistan, the middle east, algeria, brazil, and peru. cutaneous leishmaniasis in iran is caused by leishmania tropica and leishmania major . most skin lesions evolve from papular to nodular, to ulcerative form with a central depression surrounded by a raised indurate border. some lesions persist as nodules or plaques. mu...

Uterine leiomyomas are benign tumors that develop from smooth muscle cells (SMCs). The reactive oxygen species (ROS) have been shown to be involved in the signaling pathways that stimulate proliferation of a variety of cell types. Thioredoxin-1 (TRX-1) is a redox-regulating protein, which is overexpressed in various tumors. In the present study, we investigated the expressions of TRX-1 and its ...

OBJECTIVE Minimally invasive methods are used as alternatives to treat leiomyomas and include uterine artery embolization, which has emerged as a safe, effective method. This study aims to evaluate the magnetic resonance imaging predictors for a reduction in leiomyoma volume in patients undergoing uterine artery embolization. METHODS This prospective longitudinal study was performed at a univ...