We report a case of a multicentric form of Castleman's disease (CD). A thoracic computerized tomography (CT) scan showed multiple mediastinal and bilateral axillary lymph nodes. Fluoro-18 fluoro deoxyglucose ((18)F-FDG) positron emission tomography-PET/CT scan demonstrated increased (18)F-FDG accumulation in multiple lymphatic regions and in bilateral pleural areas. The histopathological sampli...

Both multicentric Castleman disease and Kaposi sarcoma are more frequently observed in HIV infected patients. The coexistence of these Human herpesvirus 8 related lesions, in the same tissue, has been observed, but literature reports are scant. On the other hand, the expression of HHV-8-LANA-1 is easily demonstrable by immunohistochemistry. This has been shown to be a powerful tool for the diag...

N.F.S., 76, black, complained of dizziness that did not improve with medication, pulsatile tinnitus and progressive hearing loss for the past 3 years in his right ear, as well as left side neck bulging for 30 years, of slow growth, painless, of fibroelastic material, non-pulsatile. On CT scan we noticed an extensive solid mass with ill-defined lobulated contours, occupying the carotid space in ...

Clinical characteristics of unilateral multicentric breast cancer (UMBC) were explored depending on aggressiveness, survival rate, disease-free period and local recurrence. The study included 296 women with breast cancer, surgically treated between 1990 and 2001. UMBC was histologically proved in 29 (9.8%) patients. Multicentricity was defined by following criteria: a) tumor with minimum one sa...