نتایج جستجو برای: multicenter
تعداد نتایج: 40857 فیلتر نتایج به سال:
BACKGROUND AND AIM COPD is a progressive and irreversible disease, thus assessing the impact of the disease on health-related quality of life (HRQOL) is important in the management of COPD. The aim of this study was to examine the relationship between HRQOL, lung function and dyspnea rating in patients with stable COPD. METHODS One hundred COPD patients (mean age = 64.76 +/- 11.43 years) were...
BACKGROUND To determine whether the addition of leucovorin to the combination 5-fluorouracil plus levamisole prolongs disease-free survival and overall survival in patients with radically resected colon cancer (Dukes' B(2-3) and C). PATIENTS AND METHODS Patients (1703) were accrued between March 1992 and February 1995 in a large-scale clinical trial within five Italian cooperative groups. Aft...
BACKGROUND Hand eczema is one of the most common skin disorders and negatively affects quality of life. However, a large-scale multicenter study investigating the clinical features of patients with hand eczema has not yet been conducted in Korea. OBJECTIVE To identify the prevalence of various hand diseases, which is defined as all cutaneous disease occurring in hands, and to investigate the ...
Genomic organization of the crested ibis MHC provides new insight into ancestral avian MHC structure
The major histocompatibility complex (MHC) plays an important role in immune response. Avian MHCs are not well characterized, only reporting highly compact Galliformes MHCs and extensively fragmented zebra finch MHC. We report the first genomic structure of an endangered Pelecaniformes (crested ibis) MHC containing 54 genes in three regions spanning ~500 kb. In contrast to the loose BG (26 loci...
PURPOSE Assessment of the feasibility to average diffusion tensor imaging (DTI) metrics of MRI data acquired in the course of a multicenter study. MATERIALS AND METHODS Sixty-one early stage Huntington's disease patients and forty healthy controls were studied using four different MR scanners at four European sites with acquisition protocols as close as possible to a given standard protocol. ...
This article focuses on a court innovation for criminally involved people who are afflicted with serious mental illnesses, such as schizophrenia, bipolar disorder, or major depression. It describes a recently developed strategy for dealing with the challenges of working with mentally ill individuals during the preand post-adjudication stages of the criminal justice process: mental health court ...
Lymph node (LN) metastasis is considered an important prognostic factor in patients with prostate cancer. The aim of this study was to determine the rate of LN metastasis among an Iranian population who underwent radical prostatectomy (RP) with pelvic LN dissection (PLND). In a retrospective review of medical records, 450 RP cases were included and the data on LN metastasis were extracted from ...
Lipomatous tumors originate from adipocytes, and represent the largest group of mesenchymal tumors. Lipomas are most likely under reported due to their insidious growth. About 13% of lipomas occur in the head and neck region. When they occur in the maxillofacial region, it is likely for the patients to be referred to the hospital for aesthetical reasons. In this multicenter study, data such as ...
Survival of Premature and Low Birth Weight Infants: A Multicenter, Prospective, Cohort Study in Iran
ABSTRACTBackground: The survival rate of preterm and low-birth-weight (LBW) infants depends on various factors such as birth weight, gestational age, and quality of care. The present study aimed at evaluating the survival rate of preterm and LBW infants, predictive factors, and the risk of mortality in three training hospitals of Mashhad and Tabriz cities.Methods: This prospective, cohort study...
OBJECTIVE To compare the analgesic efficacy of single and multiple doses of ibuprofen with that of paracetamol in patients with knee or hip osteoarthritis (IPSO study). METHOD 222 patients were randomised in a double blind, multicentre study-156 (70%) had a painful knee joint and 66 (30%) a painful hip joint. The main efficacy criterion was pain intensity assessment after a single dose (ibupr...
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